Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   Q7611_RS06965 Genome accession   NZ_CP131723
Coordinates   1385080..1387119 (-) Length   679 a.a.
NCBI ID   WP_005663494.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018C08-260     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1380080..1392119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7611_RS06955 (Q7611_06950) - 1380627..1382897 (+) 2271 WP_136429276.1 NADP-dependent malic enzyme -
  Q7611_RS06960 (Q7611_06955) - 1383125..1385050 (+) 1926 WP_342121429.1 LTA synthase family protein -
  Q7611_RS06965 (Q7611_06960) uvrB 1385080..1387119 (-) 2040 WP_005663494.1 excinuclease ABC subunit UvrB Machinery gene
  Q7611_RS06975 (Q7611_06970) zevB 1387733..1388701 (-) 969 WP_005663493.1 zinc transporter permease subunit ZevB -
  Q7611_RS06980 (Q7611_06975) zevA 1388704..1389324 (-) 621 WP_005650213.1 zinc transporter binding subunit ZevA -
  Q7611_RS06985 (Q7611_06980) - 1389649..1389954 (+) 306 WP_005650215.1 type II toxin-antitoxin system RelE/ParE family toxin -
  Q7611_RS06990 (Q7611_06985) - 1389965..1390288 (+) 324 WP_005650217.1 HigA family addiction module antitoxin -

Sequence

Protein


Download         Length: 679 a.a.        Molecular weight: 77469.98 Da        Isoelectric Point: 5.0873

>NTDB_id=792517 Q7611_RS06965 WP_005663494.1 1385080..1387119(-) (uvrB) [Haemophilus influenzae strain 2018C08-260]
MSEKINTKPFILHSDFRPSGDQPQAIEKLAENLTDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYA
EMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYL
QMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSF
GAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGYCSGIENYSRYLSG
RNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSAT
PGAYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRY
LHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYAD
SITKSMEKAITETNRRRAKQIKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQ
QIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN

Nucleotide


Download         Length: 2040 bp        

>NTDB_id=792517 Q7611_RS06965 WP_005663494.1 1385080..1387119(-) (uvrB) [Haemophilus influenzae strain 2018C08-260]
ATGTCTGAAAAAATCAACACAAAACCGTTCATTCTACATTCCGACTTTCGTCCCTCTGGCGATCAGCCACAAGCTATCGA
AAAATTGGCTGAAAATTTAACGGATGGTTTGGCACATCAAACTTTACTCGGGGTAACAGGCTCGGGGAAGACGTTTACTA
TCGCCAATGTAATCGCTCAATTAAATCGCCCCGCGATGTTACTTGCACCGAATAAAACCCTTGCTGCTCAGCTTTATGCA
GAAATGAAAGCTTTTTTTCCAGAAAATGCGGTGGAATATTTTGTGTCTTACTATGATTATTATCAGCCAGAAGCCTATGT
GCCGAGCAGTGATACATTTATTGAAAAAGATGCGTCTATTAATGATCAAATCGAACAAATGCGACTTTCTGCGACGAAAT
CTTTTCTAGAACGTCGAGACACCATCGTGGTAGCGTCTGTTTCTGCAATTTATGGTTTGGGCGATCCTGATAGCTATTTA
CAAATGATGTTGCATTTACAACAAGGTGCCATTATCGATCAACGCCAAATTTTAGCGAAGTTAGCGGAATTGCAATATAC
CCGCAATGATCAAGCATTTCAGCGTGGAACTTTCCGTGTTCGCGGAGAAATTATTGATATTTTTCCTGCTGAATCCGATG
ATCGTGCGGTGCGTATTGAATTATTTGATGATGAAATCGAGCGTTTAAGTTTATTTGATCCGCTCACTGGCAGTAGTTTT
GGTGCTGTCCCACGTTTTACGATCTATCCTAAAACTCACTATGTTACGCCAAGAGAACGTATTTTAGATGCGATAGAAAA
CATCAAAAAAGAACTGGTATCACGCCGTGAATACTTCATTAAAGAACATAAACTTTTAGAAGAACAACGTATCAGCCAGC
GTACCCAATTTGATATTGAAATGATGAATGAATTGGGCTATTGCTCGGGAATTGAAAACTACTCTCGCTATTTATCGGGA
AGAAATGAGGGCGAACCTCCACCAACATTATTTGATTATATGCCCTCTGATGCCATTTTAATTATTGATGAATCTCATGT
AACTGTGCCTCAAATTGGTGGAATGTATCGTGGCGACCGTTCACGTAAAGAAACCTTAGTCGAATATGGTTTCCGTTTGC
CGTCCGCATTGGATAATCGTCCGTTACGCTTTGAGGAATTTGAACGCTTAGCTCCGCAAACCATCTATGTTTCCGCAACA
CCAGGGGCCTATGAATTAGAGAAATCAGGTAGTGAAATCATCGATCAAGTGGTTCGCCCCACTGGTTTACTTGATCCGCT
TATTGAAATTCGTCCAGTGTCAATTCAAGTGGATGATTTACTTTCCGAAGCTCGCCAAAGAGCGGATAAAAATGAGCGAG
TTTTAGTCACAACACTCACTAAAAAAATGGCGGAAGATTTAACGGATTATTTAGATGAACACGGGATTCGTGTGCGTTAT
CTACATTCTGATATTGATACCGTGGAACGCGTCGAAATTATCCGTGATTTGCGTTTAGGCGAATTTGATGTATTGGTTGG
AATTAACTTATTACGTGAAGGTTTAGATATTCCAGAAGTGTCTCTTGTGGCGATTTTAGATGCAGACAAGGAAGGATTTT
TGCGTTCCGAACGTTCTTTAATTCAAACCATCGGTCGTGCTGCACGAAACTTAAATGGTAAAGCGATTTTATATGCAGAT
AGCATCACAAAATCCATGGAAAAAGCCATCACCGAAACTAATCGTCGTCGTGCAAAACAAATAAAATACAATGAAGAACA
TGGCATTGTGCCACAAGCATTGAATAAGAAAGTCGGTGAATTATTAGATATTGGGCAAGGTGCAAACCAAAAAGCGAAAG
CCAATAAACAACGTGGAAAAATGGCGGCAGAACCAACCGCACTTTATAATGCACCGAAAAATGCCAAAGAATATCAACAA
CAAATCAAAAAACTGGAACAACAAATGTATAAATTTGCGCAAGATTTGGAATTTGAAAAAGCCGCAGCAATTCGCGATCA
ATTACATCAATTACGTGAACAATTTGTTTTTGATAACTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(557-598)

Helicase conserved C-terminal domain (Helicase_C)

(446-549)

UvrB/uvrC motif (UVR)

(640-674)

Type III restriction enzyme, res subunit (ResIII)

(20-102)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae R6

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae D39

57.44

98.969

0.568