Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   Q7612_RS07195 Genome accession   NZ_CP131722
Coordinates   1422754..1424793 (-) Length   679 a.a.
NCBI ID   WP_075985258.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018C09-260     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1417754..1429793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7612_RS07185 (Q7612_07170) - 1418304..1420574 (+) 2271 WP_005652983.1 NADP-dependent malic enzyme -
  Q7612_RS07190 (Q7612_07175) - 1420798..1422723 (+) 1926 Protein_1365 LTA synthase family protein -
  Q7612_RS07195 (Q7612_07180) uvrB 1422754..1424793 (-) 2040 WP_075985258.1 excinuclease ABC subunit UvrB Machinery gene
  Q7612_RS07205 (Q7612_07190) zevB 1425407..1426375 (-) 969 WP_118806537.1 zinc transporter permease subunit ZevB -
  Q7612_RS07210 (Q7612_07195) zevA 1426378..1426998 (-) 621 WP_110432017.1 zinc transporter binding subunit ZevA -
  Q7612_RS07215 (Q7612_07200) - 1427323..1427628 (+) 306 WP_118806538.1 type II toxin-antitoxin system RelE/ParE family toxin -
  Q7612_RS07220 (Q7612_07205) - 1427639..1427962 (+) 324 WP_005650217.1 HigA family addiction module antitoxin -

Sequence

Protein


Download         Length: 679 a.a.        Molecular weight: 77527.97 Da        Isoelectric Point: 5.0409

>NTDB_id=792452 Q7612_RS07195 WP_075985258.1 1422754..1424793(-) (uvrB) [Haemophilus influenzae strain 2018C09-260]
MSEKINTKPFILHSDFRPSGDQPQAIEKLAENLTDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYA
EMKGFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYL
QMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSF
GAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGYCSGIENYSRYLSG
RNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSAT
PGPYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRY
LHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYAD
SITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQ
QIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN

Nucleotide


Download         Length: 2040 bp        

>NTDB_id=792452 Q7612_RS07195 WP_075985258.1 1422754..1424793(-) (uvrB) [Haemophilus influenzae strain 2018C09-260]
ATGTCTGAAAAAATCAACACAAAACCATTCATTCTGCATTCCGACTTTCGTCCCTCTGGCGATCAGCCACAAGCTATCGA
AAAATTGGCTGAAAATTTAACGGATGGTTTGGCACATCAAACTTTACTCGGGGTAACTGGCTCGGGGAAAACCTTTACTA
TCGCCAATGTAATCGCTCAATTAAATCGCCCTGCAATGTTACTTGCACCGAATAAAACCCTTGCTGCTCAGCTTTATGCA
GAAATGAAAGGTTTTTTTCCAGAAAATGCGGTGGAATATTTTGTGTCTTACTATGATTATTATCAGCCAGAAGCCTATGT
GCCGAGCAGTGATACATTTATTGAAAAAGATGCGTCTATTAATGATCAAATTGAACAAATGCGACTTTCTGCGACGAAAT
CTTTTCTAGAACGTCGAGATACCATCGTGGTAGCTTCTGTTTCTGCAATTTATGGTTTGGGCGATCCTGATAGCTATTTA
CAAATGATGTTGCATTTACAACAAGGTGCCATTATCGATCAACGCCAAATTTTAGCGAAGTTAGCGGAATTGCAATATAC
CCGAAATGATCAAGCATTTCAGCGTGGAACTTTCCGTGTTCGCGGAGAAATTATTGATATTTTCCCTGCGGAATCTGATG
ATCGTGCAGTGCGTATTGAATTATTTGATGATGAAATCGAGCGTTTAAGTTTATTTGATCCGCTCACTGGTAGTAGTTTT
GGTGCTGTCCCACGTTTTACGATCTATCCTAAAACTCACTATGTAACGCCAAGAGAACGTATTTTAGATGCGATAGAAAA
CATCAAAAAAGAACTGGTATCACGCCGTGAATACTTCATTAAAGAACATAAACTTTTAGAAGAACAGCGTATCAGCCAAC
GAACCCAATTTGATATTGAAATGATGAATGAATTGGGCTATTGCTCGGGAATTGAAAACTACTCTCGCTATTTATCGGGA
AGAAATGAGGGCGAACCACCACCAACATTATTTGATTATATGCCCTCTGATGCGATTTTAATTATTGATGAATCTCATGT
AACTGTGCCTCAAATTGGCGGGATGTATCGTGGCGACCGTTCACGTAAAGAAACCTTAGTCGAATATGGTTTCCGTTTGC
CGTCCGCATTGGATAATCGTCCGTTACGCTTTGAGGAATTTGAACGCTTAGCTCCGCAAACCATTTATGTTTCAGCAACA
CCAGGGCCTTATGAATTAGAAAAATCAGGCAGTGAAATCATCGATCAAGTGGTTCGCCCCACTGGTTTGCTTGATCCGCT
TATTGAAATTCGTCCAGTGTCTATTCAAGTGGATGATTTACTTTCCGAAGCTCGCCAAAGAGCGGATAAAAATGAGCGAG
TTTTAGTCACAACACTCACCAAGAAAATGGCGGAAGATTTAACGGATTATTTAGATGAACACGGGATTCGTGTGCGTTAT
CTACATTCTGATATTGATACCGTGGAACGCGTCGAAATTATCCGTGATTTGCGTTTAGGCGAATTTGATGTATTAGTGGG
AATTAACTTATTGCGTGAAGGTTTAGATATTCCAGAAGTGTCTCTTGTGGCGATTTTAGATGCGGACAAAGAAGGTTTTT
TGCGTTCTGAACGTTCTTTAATTCAAACCATCGGTCGTGCTGCACGAAACTTAAATGGTAAAGCGATTTTGTATGCAGAT
AGCATCACAAAATCCATGGAAAAAGCCATCACCGAAACCAATCGTCGTCGTGAAAAACAAACAAAATACAATGAAGAACA
CGGCATTGTGCCACAAGCATTAAATAAGAAAGTCGGCGAATTGTTAGATATTGGGCAAGGTGCAAACCAAAAAGCGAAAG
CCAATAAACAACGTGGAAAAATGGCGGCAGAACCAACCGCACTTTATAATGCACCAAAAAATGCCAAAGAATATCAACAA
CAAATCAAAAAACTGGAACAACAAATGTATAAATTTGCGCAAGATTTGGAATTTGAAAAAGCCGCGGCTATTCGCGATCA
ATTACATCAATTGCGTGAACAGTTTGTTTTTGATAACTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(640-674)

Type III restriction enzyme, res subunit (ResIII)

(20-102)

UvrB interaction domain (UvrB_inter)

(164-254)

Ultra-violet resistance protein B (UvrB)

(557-598)

Helicase conserved C-terminal domain (Helicase_C)

(446-549)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae R6

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae D39

57.44

98.969

0.568