Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   Q7624_RS04715 Genome accession   NZ_CP131709
Coordinates   917109..919097 (+) Length   662 a.a.
NCBI ID   WP_000610410.1    Uniprot ID   C1CR65
Organism   Streptococcus pneumoniae strain 2016S11-245     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 912109..924097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7624_RS04700 (Q7624_04695) - 913004..913744 (-) 741 WP_001096313.1 amino acid ABC transporter ATP-binding protein -
  Q7624_RS04705 (Q7624_04700) - 913744..915909 (-) 2166 WP_000726258.1 ABC transporter substrate-binding protein/permease -
  Q7624_RS04710 (Q7624_04705) - 916079..917032 (+) 954 WP_000792112.1 CPBP family intramembrane glutamic endopeptidase -
  Q7624_RS04715 (Q7624_04710) uvrB 917109..919097 (+) 1989 WP_000610410.1 excinuclease ABC subunit UvrB Machinery gene
  Q7624_RS04720 (Q7624_04715) - 919107..919670 (+) 564 WP_000639833.1 GNAT family protein -
  Q7624_RS04725 (Q7624_04720) - 919636..920124 (+) 489 WP_000237188.1 GNAT family N-acetyltransferase -
  Q7624_RS04730 (Q7624_04725) - 920197..920664 (+) 468 WP_000091545.1 8-oxo-dGTP diphosphatase -
  Q7624_RS04735 (Q7624_04730) - 920661..921176 (-) 516 WP_000159178.1 transcription repressor NadR -
  Q7624_RS04740 (Q7624_04735) - 921188..921715 (-) 528 WP_001097402.1 ECF transporter S component -
  Q7624_RS04745 (Q7624_04740) - 922011..922574 (-) 564 WP_000747408.1 ECF transporter S component -
  Q7624_RS04750 (Q7624_04745) coaC 922558..923109 (-) 552 WP_001284130.1 phosphopantothenoylcysteine decarboxylase -
  Q7624_RS04755 (Q7624_04750) coaB 923121..923810 (-) 690 WP_000699489.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75786.89 Da        Isoelectric Point: 4.6065

>NTDB_id=791277 Q7624_RS04715 WP_000610410.1 917109..919097(+) (uvrB) [Streptococcus pneumoniae strain 2016S11-245]
MINRITDNKFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVSKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=791277 Q7624_RS04715 WP_000610410.1 917109..919097(+) (uvrB) [Streptococcus pneumoniae strain 2016S11-245]
ATGATTAACCGCATTACAGATAATAAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTAGATAATATCGAGGGTGGAGAAAAAGCTCAGATTCTGATGGGGGCGACCGGAACAGGGAAGACCTATACCA
TGAGTCAGGTCATTTCCAAAGTCAATAAACCCACTCTAGTCATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTCAAGGAATTTTTCCCTGAAAATGCAGTTGAGTACTTCGTATCCTACTATGACTATTACCAGCCAGAAGCCTATGT
CCCTTCTAGTGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGTCACTCAGCGACTTCAG
CCCTATTGGAGCGCAATGATGTTATTGTCGTGGCCTCGGTCTCTTGTATCTATGGTCTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCAGGTCTTGAAATTTCCCGTGATAAACTCTTGAATGACTTGGTGGATATCCAATTTGA
GCGAAATGATATTGATTTCCAACGGGGAAGATTTCGCGTTCGTGGGGATGTGGTGGAGATTTTCCCTGCTTCCCGTGATG
AACACGCTTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAGGTTGAAGCTTTGACAGGTCAAGTCCTT
GGAGAAGTGGATCATTTAGCGATTTTCCCTGCGACTCACTTTGTGACCAATGACGACCACATGGAAGTTGCTATTGCCAA
GATTCAAGCAGAATTAGAAGAGCAACTAGCTGTCTTTGAAAAGGAAGGCAAACTGCTTGAAGCCCAGCGCTTGAAACAAC
GGACAGAGTACGATATCGAAATGCTGCGTGAGATGGGCTATACCAACGGGGTTGAGAACTATTCACGTCACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTACACACTTCTTGATTTCTTTCCAGATGATTTCTTAATCATGATTGACGAGAGCCACAT
GACCATGGGACAAATCAAGGGCATGTACAATGGAGACCGTTCTCGTAAGGAAATGTTAGTAAATTACGGTTTCCGTTTGC
CGTCTGCTCTGGACAATCGTCCTCTCCGTCGGGAGGAGTTTGAAAGCCATGTGCACCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCAGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTAGGTGAAATTAATGCTCGTGTTGAGAAGAACGAACGAACCT
TTATCACCACGTTGACCAAGAAAATGGCAGAAGACTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTCAAGTACATG
CACTCGGATATCAAGACATTGGAGCGGACTGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
CAACCTCCTTCGTGAAGGGATTGACGTTCCTGAAGTGAGCCTCGTAGCGATTCTTGATGCTGACAAGGAAGGTTTCCTTC
GTAACGAACGTGGACTCATCCAGACCATTGGACGTGCCGCCCGTAACAGTGAAGGTCATGTTATCATGTATGCGGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGCAAAATCCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCTGTGACCAAGGCAGTTTCTAAGGAAGAAGACAAGG
AAGTTGATATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTTGTTAAGAAACTCGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTAGCAGCTCAGATTCGTGATATGATGCTGGAAGTGAAGGCGTTGGATTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB/uvrC motif (UVR)

(626-660)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CR65

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

99.547

100

0.995
  uvrB Streptococcus pneumoniae D39

99.547

100

0.995
  uvrB Streptococcus pneumoniae TIGR4

99.396

100

0.994