Detailed information NTG0790073

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: MGCS35922_RS00355
• Genome accession: NZ_CP118097
• Coordinates: 55386..56297 (+)
• Length: 303 a.a.
• NCBI ID: WP_275926356.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 50386..61297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS35922_RS00330 (MGCS35922_00132)	purE	50887..51375 (+)	489	WP_012766417.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
MGCS35922_RS00335 (MGCS35922_00134)	purK	51362..52435 (+)	1074	WP_003055561.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
MGCS35922_RS00340 (MGCS35922_00136)	-	52445..53701 (+)	1257	WP_275926355.1	DUF4041 domain-containing protein	-
MGCS35922_RS00345 (MGCS35922_00138)	-	53694..53903 (+)	210	WP_014611912.1	hypothetical protein	-
MGCS35922_RS00350 (MGCS35922_00140)	purB	53952..55244 (+)	1293	WP_003056595.1	adenylosuccinate lyase	-
MGCS35922_RS00355 (MGCS35922_00142)	comR	55386..56297 (+)	912	WP_275926356.1	XRE family transcriptional regulator	Regulator
MGCS35922_RS00360 (MGCS35922_00144)	comS	56384..56482 (+)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
MGCS35922_RS00365 (MGCS35922_00146)	ruvB	56516..57514 (+)	999	WP_015057190.1	Holliday junction branch migration DNA helicase RuvB	-
MGCS35922_RS00370 (MGCS35922_00148)	-	57649..58080 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
MGCS35922_RS00375 (MGCS35922_00150)	-	58109..58510 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
MGCS35922_RS00380 (MGCS35922_00152)	-	58507..60282 (+)	1776	WP_003059359.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35981.59 Da
• Isoelectric Point: 4.7392

>NTDB_id=790073 MGCS35922_RS00355 WP_275926356.1 55386..56297(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
VLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=790073 MGCS35922_RS00355 WP_275926356.1 55386..56297(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
GTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.056	99.34	0.825
comR	Streptococcus pyogenes MGAS8232	55.298	99.67	0.551
comR	Streptococcus mutans UA159	45.819	98.68	0.452
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.233	96.37	0.446