Detailed information NTG0789926

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: Q7645_RS09860
• Genome accession: NZ_CP131641
• Coordinates: 1880381..1881607 (-)
• Length: 408 a.a.
• NCBI ID: WP_341966415.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain 2010C02-038
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1875381..1886607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7645_RS09850 (Q7645_09890)	-	1877350..1877634 (+)	285	WP_003692093.1	GIY-YIG nuclease family protein	-
Q7645_RS09855 (Q7645_09895)	yccS	1878114..1880264 (-)	2151	WP_003697785.1	YccS family putative transporter	-
Q7645_RS09860 (Q7645_09900)	pilU	1880381..1881607 (-)	1227	WP_341966415.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
Q7645_RS09865 (Q7645_09905)	pilT	1881771..1882814 (-)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
Q7645_RS09870 (Q7645_09910)	-	1882934..1883620 (+)	687	WP_003690201.1	YggS family pyridoxal phosphate-dependent enzyme	-
Q7645_RS09875 (Q7645_09915)	-	1883620..1884027 (+)	408	WP_003701818.1	hypothetical protein	-
Q7645_RS09880 (Q7645_09920)	proC	1884058..1884867 (+)	810	WP_228547131.1	pyrroline-5-carboxylate reductase	-
Q7645_RS09885 (Q7645_09925)	dksA	1885016..1885432 (+)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45667.31 Da
• Isoelectric Point: 7.5293

>NTDB_id=789926 Q7645_RS09860 WP_341966415.1 1880381..1881607(-) (pilU) [Neisseria gonorrhoeae strain 2010C02-038]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYYSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGNLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=789926 Q7645_RS09860 WP_341966415.1 1880381..1881607(-) (pilU) [Neisseria gonorrhoeae strain 2010C02-038]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACTACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCAACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	45.225	87.255	0.395
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387