Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   PUW52_RS10605 Genome accession   NZ_CP118078
Coordinates   2080998..2082323 (-) Length   441 a.a.
NCBI ID   WP_274984617.1    Uniprot ID   -
Organism   Streptococcus anginosus strain VSI16     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2075998..2087323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW52_RS10585 (PUW52_10585) - 2077325..2079901 (+) 2577 WP_274984539.1 YfhO family protein -
  PUW52_RS10600 (PUW52_10600) comE 2080249..2080998 (-) 750 WP_022526721.1 competence system response regulator transcription factor ComE Regulator
  PUW52_RS10605 (PUW52_10605) comD/comD2 2080998..2082323 (-) 1326 WP_274984617.1 GHKL domain-containing protein Regulator
  PUW52_RS10610 (PUW52_10610) - 2082341..2082487 (-) 147 WP_003029519.1 bacteriocin -
  PUW52_RS10620 (PUW52_10620) rlmH 2082769..2083248 (-) 480 WP_024052476.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PUW52_RS10625 (PUW52_10625) htrA 2083442..2084632 (+) 1191 WP_070812015.1 trypsin-like peptidase domain-containing protein Regulator
  PUW52_RS10630 (PUW52_10630) spo0J 2084687..2085454 (+) 768 WP_274984540.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 52057.75 Da        Isoelectric Point: 8.7195

>NTDB_id=789870 PUW52_RS10605 WP_274984617.1 2080998..2082323(-) (comD/comD2) [Streptococcus anginosus strain VSI16]
MVKIEFVHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFSTDLTTLIHYSIRYMMFFIQPLFFYLYFFKVKKV
RRHLSVFLALFLSLAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLIFILKAIDYFKFNFKYFKKADFKENILQ
LNFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLY
NEIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKTRDYNIEL
TFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGSAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGE
GRGLGLSNIKEIINNYEGIILDTKIEDEYFTQVIRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=789870 PUW52_RS10605 WP_274984617.1 2080998..2082323(-) (comD/comD2) [Streptococcus anginosus strain VSI16]
ATTGTGAAAATAGAATTTGTACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGCTATAAGAAAAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTCAACTGATTTAACTACTTTAA
TACATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTT
AGAAGACATCTTTCTGTATTTTTAGCACTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATTATTTCTTTAATTT
TTATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTCAAAGAGAATATTTTGCAG
TTAAACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTATCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTT
TTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGTGAAAAGTATG
AAAAAGAAGAACAAATTAAACAAAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATAGTGAGTCTGTAT
AATGAAATTCGAGGTTTTCGTCATGATTATGGAGGAATGTTGGCAAGTTTCCAATCAGCCATTCATACAGGTGATATAAA
AGAAGTAGAGCGAATTTATCAGGAAGTGCTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATT
TAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACACAAACCTTATTTAAGACGCGTGACTATAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTCAAACCCTTGCCGATTAAATTGTTAGATTTGGTTAGAATGACAAGCGTCCTTTTGAA
TAATGCCATAGAAGGATCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCT
TAGTTATTCAAAATTCACGTAAGAAACGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAA
GGACGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGA
TGAATATTTTACACAAGTAATAAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

53.846

100

0.54
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

58.901

86.621

0.51
  comD/comD2 Streptococcus pneumoniae TIGR4

48.67

85.261

0.415
  comD Streptococcus mitis NCTC 12261

48.67

85.261

0.415
  comD Streptococcus mitis SK321

48.404

85.261

0.413
  comD/comD1 Streptococcus pneumoniae Rx1

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae D39

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae R6

48.138

85.261

0.41