Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   PUW49_RS10905 Genome accession   NZ_CP118054
Coordinates   2133643..2134968 (-) Length   441 a.a.
NCBI ID   WP_207047776.1    Uniprot ID   A0AAW5TLY0
Organism   Streptococcus anginosus strain VSI37     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2128643..2139968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS10885 (PUW49_10885) - 2129970..2132546 (+) 2577 WP_024052479.1 YfhO family protein -
  PUW49_RS10900 (PUW49_10900) comE 2132894..2133643 (-) 750 WP_024052478.1 competence system response regulator transcription factor ComE Regulator
  PUW49_RS10905 (PUW49_10905) comD/comD2 2133643..2134968 (-) 1326 WP_207047776.1 GHKL domain-containing protein Regulator
  PUW49_RS10910 (PUW49_10910) - 2134986..2135132 (-) 147 WP_003029519.1 bacteriocin -
  PUW49_RS10920 (PUW49_10920) rlmH 2135414..2135893 (-) 480 WP_024052476.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PUW49_RS10925 (PUW49_10925) htrA 2136087..2137277 (+) 1191 WP_024052475.1 trypsin-like peptidase domain-containing protein Regulator
  PUW49_RS10930 (PUW49_10930) spo0J 2137332..2138099 (+) 768 WP_070672281.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 52069.81 Da        Isoelectric Point: 8.7195

>NTDB_id=789696 PUW49_RS10905 WP_207047776.1 2133643..2134968(-) (comD/comD2) [Streptococcus anginosus strain VSI37]
MVKIEFVHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFSTDLTTLIHYSIRYMMFFIQPLFFYLYFFKVKKV
RRHLSVFLALFLSLVVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLIFILKAIDYFKFNFKYFKKADFKENILQ
LNFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLY
NEIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKTRDYNIEL
TFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGE
GRGLGLSNIKEIINNYEGIILDTKIEDEYFTQVIRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=789696 PUW49_RS10905 WP_207047776.1 2133643..2134968(-) (comD/comD2) [Streptococcus anginosus strain VSI37]
ATTGTGAAAATAGAATTTGTACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGCTATAAGAAAAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTCAACTGATTTAACTACTTTAA
TACATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTT
AGAAGACATCTTTCTGTATTTTTAGCACTATTTTTATCTTTAGTTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATTATTTCTTTAATTT
TTATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTCAAAGAGAATATTTTGCAG
TTAAACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTATCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTT
TTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGTGAAAAGTATG
AAAAAGAAGAACAAATTAAACAAAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATAGTGAGTCTGTAT
AATGAAATTCGAGGTTTTCGTCATGATTATGGAGGAATGTTGGCAAGCTTCCAATCAGCCATTCATACAGGTGATATAAA
AGAAGTAGAGCGAATTTATCAGGAAGTGCTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATT
TAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACACAAACCTTATTTAAGACGCGTGACTATAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTTAAACCCTTGCCGATTAAATTGTTAGATTTGGTTAGAATGACAAGCGTCCTTTTGAA
TAATGCCATAGAAGGAGCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCT
TAGTTATTCAAAATTCACGTAAGAAACGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAA
GGACGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGA
TGAATATTTTACACAAGTAATAAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.072

100

0.542
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

59.162

86.621

0.512
  comD/comD2 Streptococcus pneumoniae TIGR4

48.404

85.261

0.413
  comD Streptococcus mitis NCTC 12261

48.404

85.261

0.413
  comD Streptococcus mitis SK321

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae Rx1

47.872

85.261

0.408
  comD/comD1 Streptococcus pneumoniae D39

47.872

85.261

0.408
  comD/comD1 Streptococcus pneumoniae R6

47.872

85.261

0.408