Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   PUW49_RS04695 Genome accession   NZ_CP118054
Coordinates   932449..933681 (+) Length   410 a.a.
NCBI ID   WP_070811463.1    Uniprot ID   -
Organism   Streptococcus anginosus strain VSI37     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 930701..951997 932449..933681 within 0


Gene organization within MGE regions


Location: 930701..951997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS04680 (PUW49_04680) - 930701..931540 (+) 840 WP_024052282.1 thymidylate synthase -
  PUW49_RS04685 (PUW49_04685) - 931725..932237 (+) 513 WP_024052281.1 dihydrofolate reductase -
  PUW49_RS04690 (PUW49_04690) - 932237..932410 (+) 174 WP_003024903.1 hypothetical protein -
  PUW49_RS04695 (PUW49_04695) clpX 932449..933681 (+) 1233 WP_070811463.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  PUW49_RS04700 (PUW49_04700) yihA 933693..934280 (+) 588 WP_070811464.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  PUW49_RS04705 (PUW49_04705) - 934461..935168 (+) 708 WP_003024892.1 glucosaminidase domain-containing protein -
  PUW49_RS04710 (PUW49_04710) - 935351..937096 (+) 1746 WP_042754049.1 ABC transporter ATP-binding protein -
  PUW49_RS04715 (PUW49_04715) - 937077..938825 (+) 1749 WP_264341785.1 ABC transporter ATP-binding protein -
  PUW49_RS04720 (PUW49_04720) - 938846..940381 (-) 1536 WP_070241652.1 ABC-F family ATP-binding cassette domain-containing protein -
  PUW49_RS04725 (PUW49_04725) - 940803..941543 (-) 741 WP_070241651.1 amino acid ABC transporter ATP-binding protein -
  PUW49_RS04730 (PUW49_04730) - 941543..943727 (-) 2185 Protein_897 ABC transporter substrate-binding protein/permease -
  PUW49_RS04735 (PUW49_04735) - 943890..944849 (+) 960 WP_070811466.1 CPBP family intramembrane glutamic endopeptidase -
  PUW49_RS04740 (PUW49_04740) uvrB 944940..946928 (+) 1989 WP_024052272.1 excinuclease ABC subunit UvrB -
  PUW49_RS04745 (PUW49_04745) - 946959..947504 (+) 546 WP_070241648.1 DUF1697 domain-containing protein -
  PUW49_RS04750 (PUW49_04750) - 947634..948376 (+) 743 Protein_901 ABC transporter ATP-binding protein -
  PUW49_RS04755 (PUW49_04755) - 948366..950006 (+) 1641 WP_264341784.1 hypothetical protein -
  PUW49_RS04760 (PUW49_04760) hemW 950132..951262 (+) 1131 WP_274995165.1 radical SAM family heme chaperone HemW -
  PUW49_RS04765 (PUW49_04765) - 951266..951997 (+) 732 WP_024052267.1 acyl-[acyl-carrier-protein] thioesterase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45665.19 Da        Isoelectric Point: 4.3940

>NTDB_id=789673 PUW49_RS04695 WP_070811463.1 932449..933681(+) (clpX) [Streptococcus anginosus strain VSI37]
MPTNRTNEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREEEDDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDSIEEIVKQRLGEKIIGFGQNNKAIDETGSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILCEPKNALVKQYQTLLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=789673 PUW49_RS04695 WP_070811463.1 932449..933681(+) (clpX) [Streptococcus anginosus strain VSI37]
ATGCCTACAAATCGTACGAATGAAATGATGGTTTATTGCTCTTTTTGTGGTAAAAGCCAAGAAGAAGTCCAAAAAATTAT
CGCAGGAAATAATGCCTTTATTTGTAATGAATGCGTGGAATTAGCGCAAGAAATCATCAGAGAGGAACTAGCAGAAGAAG
TACTAGCGGACTTGTCAGAAGTGCCAAAACCGCAAGAACTACTCAATATTTTGAATCATTATGTGATTGGGCAAGATCGT
GCTAAGCGAGCATTGGCTGTTGCTGTATACAATCACTATAAACGTATCAATTTTCACGATAATCGTGAAGAAGAGGATGA
TGTCGAATTACAAAAATCCAATATTCTTATGATTGGGCCAACTGGTTCTGGTAAGACTTTTCTTGCTCAAACCTTGGCGA
AAAGTCTGAATGTTCCTTTTGCGATTGCAGATGCGACAGCTTTGACAGAAGCTGGGTATGTCGGAGAAGATGTTGAAAAT
ATTCTCTTGAAACTCTTGCAAGCAGCAGATTTCAATATTGAGCGTGCAGAACGTGGTATCATCTATGTAGATGAGATTGA
CAAAATTGCGAAGAAAAGCGAAAACGTGTCTATTACTCGCGATGTGTCTGGTGAAGGCGTTCAGCAAGCGCTCCTCAAGA
TTATTGAAGGAACTGTAGCCAGCGTACCTCCGCAAGGCGGTCGCAAGCACCCTCAACAAGAAATGATTCAAGTAGATACC
AAGAATATTCTCTTTATCGTTGGTGGTGCATTTGACAGTATTGAAGAAATTGTCAAACAACGTCTAGGCGAAAAAATTAT
CGGTTTTGGTCAAAATAATAAAGCCATTGATGAAACTGGTTCTTATATGCAAGAAATCATCTCTGAAGATATTCAAAAAT
TTGGTTTGATTCCGGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTGACAGTTGATGATTTGGTGCGA
ATCCTGTGCGAACCAAAGAATGCTTTAGTGAAGCAATATCAGACTCTCCTTTCTTATGACGATGTTAAACTAGAGTTTGA
TGATGATGCTCTTCAGGAAATTGCTAACAAGGCCATTGAACGCAAGACAGGTGCGCGTGGATTACGTTCAATCATTGAGG
AAACTATGATGGATGTTATGTTTGAAGTTCCAAGTCAAGAAAATGTGAAGCTGGTACGGATTACCAAGGAAGCAGTTGAT
GGAACGGATAAGCCGATTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.96

98.049

0.568