Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   PUW70_RS02405 Genome accession   NZ_CP118029
Coordinates   456988..458043 (+) Length   351 a.a.
NCBI ID   WP_024052081.1    Uniprot ID   A0A413KQY5
Organism   Streptococcus anginosus strain VSI68     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 451988..463043
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW70_RS02375 (PUW70_02375) - 452509..453144 (-) 636 WP_024052085.1 YigZ family protein -
  PUW70_RS02380 (PUW70_02380) comFA/cflA 453201..454502 (+) 1302 WP_024052084.1 DEAD/DEAH box helicase Machinery gene
  PUW70_RS02385 (PUW70_02385) comFC/cflB 454499..455164 (+) 666 WP_024052083.1 ComF family protein Machinery gene
  PUW70_RS02390 (PUW70_02390) raiA 455242..455784 (+) 543 WP_003025754.1 ribosome-associated translation inhibitor RaiA -
  PUW70_RS02395 (PUW70_02395) rsmD 455972..456520 (+) 549 WP_171021853.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  PUW70_RS02400 (PUW70_02400) coaD 456510..457007 (+) 498 WP_021001374.1 pantetheine-phosphate adenylyltransferase -
  PUW70_RS02405 (PUW70_02405) sepM 456988..458043 (+) 1056 WP_024052081.1 SepM family pheromone-processing serine protease Regulator
  PUW70_RS02410 (PUW70_02410) - 458182..458745 (+) 564 WP_024052080.1 YutD-like domain-containing protein -
  PUW70_RS02415 (PUW70_02415) rlmN 458786..459868 (+) 1083 WP_024052079.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  PUW70_RS02420 (PUW70_02420) - 459861..460391 (+) 531 WP_024052078.1 VanZ family protein -
  PUW70_RS02425 (PUW70_02425) trpB 460752..461960 (+) 1209 Protein_436 tryptophan synthase subunit beta -
  PUW70_RS02430 (PUW70_02430) cclA/cilC 462121..462780 (-) 660 WP_024052075.1 A24 family peptidase Machinery gene

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 38290.25 Da        Isoelectric Point: 10.1906

>NTDB_id=789234 PUW70_RS02405 WP_024052081.1 456988..458043(+) (sepM) [Streptococcus anginosus strain VSI68]
MEKPRNKFKKWPIIAVVGVILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATLAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=789234 PUW70_RS02405 WP_024052081.1 456988..458043(+) (sepM) [Streptococcus anginosus strain VSI68]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAGTAGTAGGGGTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCGGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTATAATTTTGTAACGGTTGGAATTCAGCATGCGACCCTCGCTCATTTGGTTTATGCTTGGCTG
ACACCTTTTACGGATATTTATTCGGCGAAGGATTTGACTGGTGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACGTCGCAAAACCTAGCTAAATACCAAGGGTTGAAAAAAGCTGGCAAAGACATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGTATTTTAAATATTGCAGATACCGTGACAGGTGTGAAT
GATAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTCGGAGCGCAAAAGATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAGTCTGCTACAGGTAAAATTATTAAACTTGAAAATGGGAAAAACGGGATTGGCATTAGTT
TGATTGACCGAACAGAAGTCACAAGCAACACACCAATTGAATTTTCAACTGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGCAGAAATATTGCTGGGACAGGTTCGAT
TGACCGAGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAACTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAGAG
CACAAAAAAGTCGTAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(234-307)

PDZ domain (PDZ_2)

(133-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A413KQY5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

64.223

97.151

0.624