Detailed information NTG0788182

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: Q6379_RS10410
• Genome accession: NZ_CP130892
• Coordinates: 1962921..1964147 (-)
• Length: 408 a.a.
• NCBI ID: WP_003690199.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain NJ204705
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1957921..1969147

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q6379_RS10400 (Q6379_10400)	-	1959886..1960170 (+)	285	WP_003692093.1	GIY-YIG nuclease family protein	-
Q6379_RS10405 (Q6379_10405)	yccS	1960654..1962804 (-)	2151	WP_003697785.1	YccS family putative transporter	-
Q6379_RS10410 (Q6379_10410)	pilU	1962921..1964147 (-)	1227	WP_003690199.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
Q6379_RS10415 (Q6379_10415)	pilT	1964311..1965354 (-)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
Q6379_RS10420 (Q6379_10420)	-	1965474..1966160 (+)	687	WP_003699139.1	YggS family pyridoxal phosphate-dependent enzyme	-
Q6379_RS10425 (Q6379_10425)	-	1966160..1966567 (+)	408	WP_003690202.1	hypothetical protein	-
Q6379_RS10430 (Q6379_10430)	proC	1966616..1967407 (+)	792	WP_003696395.1	pyrroline-5-carboxylate reductase	-
Q6379_RS10435 (Q6379_10435)	dksA	1967556..1967972 (+)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-
Q6379_RS10440 (Q6379_10440)	-	1967987..1968259 (+)	273	WP_162855536.1	hypothetical protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45672.29 Da
• Isoelectric Point: 7.3203

>NTDB_id=788182 Q6379_RS10410 WP_003690199.1 1962921..1964147(-) (pilU) [Neisseria gonorrhoeae strain NJ204705]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGTHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=788182 Q6379_RS10410 WP_003690199.1 1962921..1964147(-) (pilU) [Neisseria gonorrhoeae strain NJ204705]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCACACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387