Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   OHB58_RS12445 Genome accession   NZ_CP130716
Coordinates   2787831..2789963 (-) Length   710 a.a.
NCBI ID   WP_371652060.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00150     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2782831..2794963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB58_RS12425 (OHB58_12375) - 2783387..2783692 (-) 306 WP_371652055.1 hypothetical protein -
  OHB58_RS12430 (OHB58_12380) - 2783832..2784812 (-) 981 WP_371652056.1 TerC family protein -
  OHB58_RS12435 (OHB58_12385) - 2785089..2787011 (-) 1923 WP_371652058.1 TerD family protein -
  OHB58_RS12440 (OHB58_12390) - 2787134..2787712 (-) 579 WP_067157856.1 TerD family protein -
  OHB58_RS12445 (OHB58_12395) uvrB 2787831..2789963 (-) 2133 WP_371652060.1 excinuclease ABC subunit UvrB Machinery gene
  OHB58_RS12450 (OHB58_12400) - 2790036..2790896 (-) 861 WP_371652061.1 MHYT domain-containing protein -
  OHB58_RS12455 (OHB58_12405) - 2791175..2791753 (+) 579 WP_371652062.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  OHB58_RS12460 (OHB58_12410) - 2791799..2792188 (-) 390 WP_371652063.1 cupin domain-containing protein -
  OHB58_RS12465 (OHB58_12415) - 2792385..2793290 (+) 906 WP_371652064.1 pseudouridine-5'-phosphate glycosidase -
  OHB58_RS12470 (OHB58_12420) - 2793287..2794246 (+) 960 WP_371652065.1 carbohydrate kinase family protein -
  OHB58_RS12475 (OHB58_12425) - 2794269..2794910 (-) 642 WP_371652066.1 uridine kinase -

Sequence

Protein


Download         Length: 710 a.a.        Molecular weight: 79986.87 Da        Isoelectric Point: 4.9028

>NTDB_id=787075 OHB58_RS12445 WP_371652060.1 2787831..2789963(-) (uvrB) [Streptomyces sp. NBC_00150]
MRPVSKIERTVAPFEVVSPYQPSGDQPAAIAELERRIRAGEKDVVLLGATGTGKSATTAWMIEKLQRPTLVMAPNKTLAA
QLANEFRELLPNNAVEYFVSYYDYYQPEAYVPQSDTYIEKDSSINEEVERLRHSATNSLLTRRDVIVVASVSCIYGLGTP
QEYVDRMVPLKVGEEIDRDQLLRRFVDIQYTRNDVAFSRGTFRVRGDTIEIFPVYEELAVRIEMFGDEIEALSTLHPLTG
EIISEDRELYVFPASHYVAGPERMEKAVTGIEQELEQRLAELDKQGKLLEAQRLRMRTTYDIEMLRQIGSCSGVENYSMH
FDGRDPGTAPNTLLDYFPDDFLLVLDESHVTVPQIGAMYEGDASRKRTLVDHGFRLPSAMDNRPLKWEEFLGRVDQTVYL
SATPGKYELSRGDGFVEQIIRPTGLVDPEVVVKPTEGQIDDLVHEIRKRTEKDERVLVTTLTKKMAEDLTDYFLEMGIQV
RYLHSDVDTLRRVELLRELRAGEFDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSGTSLIQTIGRAARNVSGQVHMY
ADRITPSMEKAIEETNRRREKQVAYNKERGIDPQPLRKKINDIVATIAREEVDTEQLLGSGYRKAKDGKGAKAPVPALGG
KAAKSKAKAGKGGEVLTDRPAAELAEQIEEMTDRMRAAAAELQFEIAARLRDEVGELKKELRQMREAGQA

Nucleotide


Download         Length: 2133 bp        

>NTDB_id=787075 OHB58_RS12445 WP_371652060.1 2787831..2789963(-) (uvrB) [Streptomyces sp. NBC_00150]
ATGCGGCCCGTTTCCAAGATCGAACGTACGGTGGCGCCTTTCGAGGTCGTCAGCCCCTACCAGCCCAGCGGCGACCAGCC
GGCGGCCATCGCCGAGCTGGAGCGGCGCATCCGTGCAGGTGAGAAGGATGTCGTCCTGCTGGGCGCGACCGGCACCGGAA
AGTCGGCGACGACTGCCTGGATGATCGAGAAGCTCCAGCGCCCCACGCTCGTCATGGCGCCGAACAAGACGCTGGCGGCC
CAGCTGGCGAACGAGTTCCGCGAGCTCCTGCCCAACAACGCCGTCGAGTACTTCGTGTCGTACTACGACTACTACCAGCC
CGAGGCGTACGTCCCGCAGTCGGACACGTACATCGAGAAGGACTCCTCGATCAACGAGGAGGTCGAGCGGCTGCGCCACT
CGGCGACGAACTCGCTGCTGACCCGCCGCGACGTGATCGTCGTGGCCTCCGTCTCGTGCATCTACGGCCTGGGCACGCCG
CAGGAGTACGTCGACCGGATGGTGCCGCTGAAGGTCGGCGAGGAGATCGACCGCGACCAGCTGCTGCGCCGCTTCGTCGA
CATCCAGTACACGCGCAACGACGTGGCCTTCTCGCGCGGCACGTTCCGGGTGCGCGGTGACACCATCGAGATCTTCCCGG
TCTACGAGGAGCTGGCCGTCCGGATCGAGATGTTCGGCGACGAGATCGAGGCGCTGTCCACGCTCCACCCGCTCACCGGC
GAGATCATCAGCGAGGACCGGGAGCTCTACGTCTTCCCCGCCAGCCACTACGTGGCAGGGCCGGAGCGCATGGAGAAGGC
GGTCACCGGCATCGAGCAGGAGCTGGAGCAGCGCCTGGCCGAGCTGGACAAGCAGGGCAAGCTCCTGGAGGCCCAGCGGC
TGCGGATGCGCACCACGTACGACATCGAGATGCTGCGCCAGATCGGCAGCTGCTCGGGCGTCGAGAACTACTCGATGCAC
TTCGACGGCCGCGACCCCGGCACCGCGCCCAACACGCTGCTCGACTACTTCCCGGACGACTTCCTGCTCGTCCTCGACGA
GTCGCACGTGACCGTCCCCCAGATCGGCGCGATGTACGAGGGGGACGCCTCCCGCAAGCGCACCCTGGTCGACCACGGCT
TCCGGCTGCCCTCCGCGATGGACAACCGGCCGCTGAAGTGGGAGGAGTTCCTGGGTCGCGTCGACCAGACCGTCTACCTC
TCGGCGACGCCCGGCAAGTACGAGCTGTCGCGCGGCGACGGCTTCGTGGAGCAGATCATCCGCCCCACCGGCCTGGTCGA
CCCGGAGGTCGTGGTCAAGCCCACCGAGGGGCAGATCGACGACCTGGTGCACGAGATCCGCAAGCGCACCGAGAAGGACG
AGCGCGTCCTGGTCACCACCCTCACCAAGAAGATGGCCGAGGACCTGACCGACTACTTCCTGGAGATGGGCATCCAGGTG
CGGTACCTGCACAGCGACGTCGACACGCTGCGCCGCGTCGAGCTGCTGCGGGAGCTGCGGGCGGGCGAGTTCGACGTGCT
GGTCGGCATCAACCTGCTCCGCGAGGGCCTGGACCTGCCCGAGGTGTCGCTGGTCGCGATCCTCGACGCCGACAAGGAGG
GCTTCCTCCGCTCGGGCACCTCGCTGATCCAGACCATCGGCCGCGCGGCGCGCAACGTCTCCGGCCAGGTCCACATGTAC
GCCGACAGGATCACCCCGTCGATGGAGAAGGCCATCGAGGAGACCAACCGCCGCCGGGAGAAGCAGGTCGCGTACAACAA
GGAGCGCGGCATCGACCCGCAGCCGCTGCGGAAGAAGATCAACGACATCGTCGCGACCATCGCGCGCGAGGAGGTCGACA
CCGAGCAGCTGCTCGGCTCCGGCTACCGCAAGGCGAAGGACGGCAAGGGCGCCAAGGCGCCGGTCCCCGCGCTCGGTGGC
AAGGCGGCGAAGTCGAAGGCGAAGGCGGGCAAGGGCGGCGAGGTCCTCACCGACCGCCCGGCCGCCGAACTCGCCGAGCA
GATCGAGGAGATGACCGACCGAATGCGGGCCGCCGCCGCCGAGTTGCAGTTCGAGATCGCCGCCAGATTGCGCGACGAAG
TCGGGGAGCTGAAGAAGGAGTTGCGGCAGATGCGGGAGGCGGGTCAGGCCTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(666-700)

Type III restriction enzyme, res subunit (ResIII)

(25-145)

Helicase conserved C-terminal domain (Helicase_C)

(440-551)

UvrB interaction domain (UvrB_inter)

(169-257)

Ultra-violet resistance protein B (UvrB)

(559-600)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

58.055

97.042

0.563
  uvrB Streptococcus pneumoniae R6

58.055

97.042

0.563
  uvrB Streptococcus pneumoniae D39

58.055

97.042

0.563