Detailed information
Bioinformatically predicted
Overview
| Name | ccpA | Type | Regulator |
| Locus tag | MGCS35957_RS02895 | Genome accession | NZ_CP117288 |
| Coordinates | 545715..546716 (+) | Length | 333 a.a. |
| NCBI ID | WP_003049927.1 | Uniprot ID | A0A9X5LWR8 |
| Organism | Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 468924..548930 | 545715..546716 | within | 0 |
Gene organization within MGE regions
Location: 468924..548930
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MGCS35957_RS02475 (MGCS35957_01012) | metG | 469141..471138 (+) | 1998 | WP_049520067.1 | methionine--tRNA ligase | - |
| MGCS35957_RS02480 (MGCS35957_01014) | nrdF | 471671..472684 (+) | 1014 | WP_003055629.1 | class 1b ribonucleoside-diphosphate reductase subunit beta | - |
| MGCS35957_RS02485 (MGCS35957_01016) | nrdI | 472688..473161 (+) | 474 | WP_003055616.1 | class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI | - |
| MGCS35957_RS02490 (MGCS35957_01018) | nrdE | 473145..475331 (+) | 2187 | WP_003055626.1 | class 1b ribonucleoside-diphosphate reductase subunit alpha | - |
| MGCS35957_RS02495 (MGCS35957_01020) | brnQ | 475629..476963 (+) | 1335 | WP_003055639.1 | branched-chain amino acid transport system II carrier protein | - |
| MGCS35957_RS02500 (MGCS35957_01024) | - | 477362..477715 (+) | 354 | WP_084916410.1 | hypothetical protein | - |
| MGCS35957_RS02505 (MGCS35957_01026) | - | 478026..478262 (+) | 237 | WP_032460623.1 | DUF2829 domain-containing protein | - |
| MGCS35957_RS02510 (MGCS35957_01028) | - | 478255..478953 (+) | 699 | WP_003054338.1 | 3-oxoacyl-ACP reductase | - |
| MGCS35957_RS02515 (MGCS35957_01030) | - | 478950..479192 (+) | 243 | WP_042357856.1 | DUF3977 family protein | - |
| MGCS35957_RS02520 (MGCS35957_01032) | - | 479210..479659 (+) | 450 | WP_084916411.1 | ASCH domain-containing protein | - |
| MGCS35957_RS02525 (MGCS35957_01034) | - | 479661..480620 (+) | 960 | WP_003054341.1 | Gfo/Idh/MocA family oxidoreductase | - |
| MGCS35957_RS02530 (MGCS35957_01036) | - | 480954..482291 (+) | 1338 | WP_046159276.1 | MFS transporter | - |
| MGCS35957_RS02535 (MGCS35957_01038) | glmU | 482463..483845 (+) | 1383 | WP_084916412.1 | bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU | - |
| MGCS35957_RS02540 (MGCS35957_01040) | - | 483876..484430 (+) | 555 | WP_003059987.1 | NUDIX hydrolase | - |
| MGCS35957_RS02545 (MGCS35957_01042) | macP | 484431..484682 (+) | 252 | WP_003054365.1 | cell wall synthase accessory phosphoprotein MacP | - |
| MGCS35957_RS02550 (MGCS35957_01044) | - | 484700..485395 (+) | 696 | WP_003054376.1 | 5'-methylthioadenosine/adenosylhomocysteine nucleosidase | - |
| MGCS35957_RS02555 (MGCS35957_01046) | - | 485468..486115 (-) | 648 | WP_003059888.1 | metal-dependent transcriptional regulator | - |
| MGCS35957_RS02560 (MGCS35957_01050) | - | 486261..487193 (+) | 933 | WP_003062287.1 | metal ABC transporter substrate-binding protein | - |
| MGCS35957_RS02565 (MGCS35957_01052) | - | 487258..487983 (+) | 726 | WP_003054363.1 | metal ABC transporter ATP-binding protein | - |
| MGCS35957_RS02570 (MGCS35957_01054) | - | 487984..488832 (+) | 849 | WP_003054335.1 | metal ABC transporter permease | - |
| MGCS35957_RS02575 (MGCS35957_01056) | - | 488963..489769 (-) | 807 | WP_003054349.1 | peptidylprolyl isomerase | - |
| MGCS35957_RS02580 (MGCS35957_01058) | - | 489987..492395 (+) | 2409 | WP_037590009.1 | DNA translocase FtsK | - |
| MGCS35957_RS02585 (MGCS35957_01060) | - | 492464..492817 (-) | 354 | WP_037587264.1 | DUF3397 domain-containing protein | - |
| MGCS35957_RS02590 (MGCS35957_01062) | rplK | 493060..493485 (+) | 426 | WP_003049875.1 | 50S ribosomal protein L11 | - |
| MGCS35957_RS02595 (MGCS35957_01064) | rplA | 493591..494280 (+) | 690 | WP_003049876.1 | 50S ribosomal protein L1 | - |
| MGCS35957_RS02600 (MGCS35957_01066) | - | 494783..494950 (-) | 168 | WP_003054374.1 | hypothetical protein | - |
| MGCS35957_RS02605 (MGCS35957_01068) | pyrH | 495232..495960 (+) | 729 | WP_003049878.1 | UMP kinase | - |
| MGCS35957_RS02610 (MGCS35957_01070) | frr | 495989..496546 (+) | 558 | WP_003054381.1 | ribosome recycling factor | - |
| MGCS35957_RS02615 (MGCS35957_01072) | - | 496655..497512 (+) | 858 | WP_003054345.1 | S1 RNA-binding domain-containing protein | - |
| MGCS35957_RS02620 (MGCS35957_01074) | msrA | 497585..498094 (+) | 510 | WP_003054395.1 | peptide-methionine (S)-S-oxide reductase MsrA | - |
| MGCS35957_RS02625 (MGCS35957_01076) | - | 498091..498306 (+) | 216 | WP_003054340.1 | YozE family protein | - |
| MGCS35957_RS02630 (MGCS35957_01078) | - | 498466..499701 (+) | 1236 | WP_003054361.1 | LysM domain-containing protein | - |
| MGCS35957_RS02635 (MGCS35957_01080) | - | 500012..501784 (+) | 1773 | WP_003054339.1 | oleate hydratase | - |
| MGCS35957_RS02640 (MGCS35957_01082) | - | 501945..503006 (+) | 1062 | WP_003054347.1 | PhoH family protein | - |
| MGCS35957_RS02645 (MGCS35957_01084) | - | 503053..503628 (+) | 576 | WP_003054351.1 | uracil-DNA glycosylase family protein | - |
| MGCS35957_RS02650 (MGCS35957_01086) | ybeY | 503787..504284 (+) | 498 | WP_003054373.1 | rRNA maturation RNase YbeY | - |
| MGCS35957_RS02655 (MGCS35957_01088) | - | 504265..504672 (+) | 408 | WP_003054389.1 | diacylglycerol kinase | - |
| MGCS35957_RS02660 (MGCS35957_01090) | era | 504793..505689 (+) | 897 | WP_002985743.1 | GTPase Era | - |
| MGCS35957_RS02665 (MGCS35957_01092) | - | 505710..506186 (+) | 477 | WP_002993018.1 | NUDIX domain-containing protein | - |
| MGCS35957_RS02670 (MGCS35957_01094) | - | 506495..506746 (-) | 252 | WP_080589767.1 | hypothetical protein | - |
| MGCS35957_RS02675 | - | 507047..507265 (+) | 219 | WP_072135532.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| MGCS35957_RS02680 (MGCS35957_01098) | - | 507546..509259 (-) | 1714 | Protein_484 | peptide cleavage/export ABC transporter | - |
| MGCS35957_RS02685 (MGCS35957_01100) | - | 509557..509784 (+) | 228 | WP_022554332.1 | Blp family class II bacteriocin | - |
| MGCS35957_RS02690 (MGCS35957_01102) | - | 509833..510150 (+) | 318 | WP_002994587.1 | hypothetical protein | - |
| MGCS35957_RS02695 (MGCS35957_01104) | - | 510333..511354 (+) | 1022 | Protein_487 | IS3 family transposase | - |
| MGCS35957_RS02700 (MGCS35957_01106) | - | 511568..512986 (+) | 1419 | WP_231873805.1 | IS1182 family transposase | - |
| MGCS35957_RS02710 (MGCS35957_01110) | comE/blpR | 514607..515356 (+) | 750 | WP_030126108.1 | response regulator transcription factor | Regulator |
| MGCS35957_RS02720 (MGCS35957_01114) | - | 515698..516831 (-) | 1134 | WP_275902597.1 | ISAs1-like element IS1548 family transposase | - |
| MGCS35957_RS02725 (MGCS35957_01116) | - | 517061..518017 (+) | 957 | WP_046166194.1 | GHKL domain-containing protein | - |
| MGCS35957_RS02730 (MGCS35957_01118) | - | 518165..518290 (-) | 126 | WP_011017462.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | - |
| MGCS35957_RS02735 (MGCS35957_01122) | - | 518367..519731 (-) | 1365 | WP_084916305.1 | bacteriocin secretion accessory protein | - |
| MGCS35957_RS02740 (MGCS35957_01124) | comA/nlmT | 519742..521895 (-) | 2154 | WP_084916306.1 | peptide cleavage/export ABC transporter | Regulator |
| MGCS35957_RS02745 (MGCS35957_01126) | - | 522182..522409 (+) | 228 | WP_002992018.1 | Blp family class II bacteriocin | - |
| MGCS35957_RS02750 (MGCS35957_01128) | - | 522422..522622 (+) | 201 | WP_003060803.1 | class IIb bacteriocin, lactobin A/cerein 7B family | - |
| MGCS35957_RS02755 (MGCS35957_01130) | - | 522916..523110 (+) | 195 | WP_002990768.1 | hypothetical protein | - |
| MGCS35957_RS02760 (MGCS35957_01132) | - | 523158..523439 (+) | 282 | WP_011054252.1 | hypothetical protein | - |
| MGCS35957_RS02765 (MGCS35957_01134) | - | 523633..524043 (+) | 411 | WP_003061293.1 | hypothetical protein | - |
| MGCS35957_RS02770 | - | 524290..524537 (+) | 248 | Protein_501 | hypothetical protein | - |
| MGCS35957_RS02775 (MGCS35957_01136) | - | 524559..524813 (+) | 255 | WP_014612089.1 | CPBP family intramembrane glutamic endopeptidase | - |
| MGCS35957_RS02780 (MGCS35957_01140) | - | 525198..525962 (+) | 765 | WP_003061232.1 | hypothetical protein | - |
| MGCS35957_RS02785 (MGCS35957_01142) | - | 526112..527054 (-) | 943 | Protein_504 | hypothetical protein | - |
| MGCS35957_RS02790 | shp2 | 527123..527191 (-) | 69 | WP_134771781.1 | peptide pheromone SHP2 | - |
| MGCS35957_RS02795 (MGCS35957_01144) | rgg2 | 527281..528135 (+) | 855 | Protein_506 | quorum-sensing system transcriptional regulator Rgg2 | - |
| MGCS35957_RS02800 (MGCS35957_01146) | mutM | 528317..529144 (+) | 828 | WP_084916308.1 | DNA-formamidopyrimidine glycosylase | - |
| MGCS35957_RS02805 (MGCS35957_01148) | coaE | 529123..529734 (+) | 612 | WP_172453883.1 | dephospho-CoA kinase | - |
| MGCS35957_RS02810 (MGCS35957_01150) | - | 530102..530803 (+) | 702 | WP_003056868.1 | ABC transporter ATP-binding protein | - |
| MGCS35957_RS02815 (MGCS35957_01152) | - | 530793..532430 (+) | 1638 | WP_022554345.1 | hypothetical protein | - |
| MGCS35957_RS02820 (MGCS35957_01154) | - | 532540..534042 (+) | 1503 | WP_084916309.1 | helicase HerA-like domain-containing protein | - |
| MGCS35957_RS02825 (MGCS35957_01156) | - | 534206..535423 (+) | 1218 | WP_223846048.1 | multidrug efflux MFS transporter | - |
| MGCS35957_RS02830 | rpmG | 535420..535566 (+) | 147 | WP_003047126.1 | 50S ribosomal protein L33 | - |
| MGCS35957_RS02835 (MGCS35957_01158) | secG | 535612..535848 (+) | 237 | WP_003047129.1 | preprotein translocase subunit SecG | - |
| MGCS35957_RS02840 (MGCS35957_01160) | rnr | 535945..538275 (+) | 2331 | WP_084916311.1 | ribonuclease R | - |
| MGCS35957_RS02845 (MGCS35957_01162) | smpB | 538278..538745 (+) | 468 | WP_022554349.1 | SsrA-binding protein SmpB | - |
| MGCS35957_RS02850 (MGCS35957_01164) | - | 538924..539280 (+) | 357 | WP_003053910.1 | hypothetical protein | - |
| MGCS35957_RS02855 (MGCS35957_01166) | - | 539373..540721 (+) | 1349 | WP_111678974.1 | IS3 family transposase | - |
| MGCS35957_RS02860 (MGCS35957_01168) | - | 540778..541704 (-) | 927 | WP_003053920.1 | glycosyltransferase family 2 protein | - |
| MGCS35957_RS11140 (MGCS35957_01170) | - | 541841..543025 (-) | 1185 | Protein_520 | DNA/RNA non-specific endonuclease | - |
| MGCS35957_RS02880 (MGCS35957_01172) | - | 543363..543737 (-) | 375 | WP_046177445.1 | VOC family protein | - |
| MGCS35957_RS02885 (MGCS35957_01174) | - | 543747..544412 (-) | 666 | WP_003058626.1 | NAD(P)H-dependent oxidoreductase | - |
| MGCS35957_RS02890 (MGCS35957_01176) | - | 544456..545541 (-) | 1086 | WP_003058632.1 | Xaa-Pro peptidase family protein | - |
| MGCS35957_RS02895 (MGCS35957_01178) | ccpA | 545715..546716 (+) | 1002 | WP_003049927.1 | catabolite control protein A | Regulator |
| MGCS35957_RS02900 (MGCS35957_01180) | - | 546870..548333 (+) | 1464 | WP_012766666.1 | alpha-amylase | - |
Sequence
Protein
Download Length: 333 a.a. Molecular weight: 36683.74 Da Isoelectric Point: 5.7248
>NTDB_id=783378 MGCS35957_RS02895 WP_003049927.1 545715..546716(+) (ccpA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPIVLAGTVDLDHQLPS
VNIDYKAAVSNVVDILAENHQSIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPIVLAGTVDLDHQLPS
VNIDYKAAVSNVVDILAENHQSIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK
Nucleotide
Download Length: 1002 bp
>NTDB_id=783378 MGCS35957_RS02895 WP_003049927.1 545715..546716(+) (ccpA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957]
ATGAATACAGATGATACCATCACGATTTATGACGTTGCCCGTGAAGCTGGTGTTTCTATGGCAACTGTTAGTCGTGTTGT
TAATGGCAATAAAAACGTTAAGGAAAACACGCGTAAGAAAGTTTTAGAAGTCATTGACCGCCTAGATTATCGTCCAAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAAACAACAACCGTCGGGGTTGTGATTCCGAATATTGCAAACAGTTATTTTTCT
ATTTTAGCCAAAGGTATTGATGATATCGCCGCTATGTATAAATATAATATTGTACTTGCCTCTAGTGATGAGGATGATGA
CAAGGAGGTTAACGTTGTTAATACCCTCTTTGCTAAGCAAGTTGACGGTATTATCTTTATGGGGCACCACTTGACTGAAA
AAATCCGTGCGGAATTTTCACGCTCACGCACCCCGATTGTTTTAGCAGGGACAGTTGACCTTGATCATCAATTACCAAGT
GTTAATATTGACTATAAGGCAGCTGTGTCTAATGTGGTTGATATTTTGGCAGAAAACCATCAGAGCATTGCCTTTGTGTC
AGGACCACTTATTGATGACATCAATGGTAAAGTACGTTTGGCGGGTTACAAAGAAGGCTTGAAGCACAACAAACTTGACT
TCAAAGAAGGACTTGTTTTTGAAGCTAACTATTCTTATAAAGAAGGTTTTGAATTGGCACAACGTGTGATTAACTCAGGA
GCAACAGCAGCTTATGTGGCTGAAGATGAGTTAGCAGCGGGTCTTTTAAATGGTTTGTTTGAAGCAGGCAAACGCGTTCC
AGAAGATTTTGAAATCATCACAAGCAATGATTCACCAGTTGTTCAATATACCCGTCCAAACTTGAGTTCTATCAGCCAAC
CCGTTTACGACTTGGGAGCTGTCAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGCGGAACCACTAAATAG
ATGAATACAGATGATACCATCACGATTTATGACGTTGCCCGTGAAGCTGGTGTTTCTATGGCAACTGTTAGTCGTGTTGT
TAATGGCAATAAAAACGTTAAGGAAAACACGCGTAAGAAAGTTTTAGAAGTCATTGACCGCCTAGATTATCGTCCAAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAAACAACAACCGTCGGGGTTGTGATTCCGAATATTGCAAACAGTTATTTTTCT
ATTTTAGCCAAAGGTATTGATGATATCGCCGCTATGTATAAATATAATATTGTACTTGCCTCTAGTGATGAGGATGATGA
CAAGGAGGTTAACGTTGTTAATACCCTCTTTGCTAAGCAAGTTGACGGTATTATCTTTATGGGGCACCACTTGACTGAAA
AAATCCGTGCGGAATTTTCACGCTCACGCACCCCGATTGTTTTAGCAGGGACAGTTGACCTTGATCATCAATTACCAAGT
GTTAATATTGACTATAAGGCAGCTGTGTCTAATGTGGTTGATATTTTGGCAGAAAACCATCAGAGCATTGCCTTTGTGTC
AGGACCACTTATTGATGACATCAATGGTAAAGTACGTTTGGCGGGTTACAAAGAAGGCTTGAAGCACAACAAACTTGACT
TCAAAGAAGGACTTGTTTTTGAAGCTAACTATTCTTATAAAGAAGGTTTTGAATTGGCACAACGTGTGATTAACTCAGGA
GCAACAGCAGCTTATGTGGCTGAAGATGAGTTAGCAGCGGGTCTTTTAAATGGTTTGTTTGAAGCAGGCAAACGCGTTCC
AGAAGATTTTGAAATCATCACAAGCAATGATTCACCAGTTGTTCAATATACCCGTCCAAACTTGAGTTCTATCAGCCAAC
CCGTTTACGACTTGGGAGCTGTCAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGCGGAACCACTAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccpA | Streptococcus gordonii str. Challis substr. CH1 |
77.778 |
100 |
0.778 |
| ccpA | Streptococcus pneumoniae D39 |
75.976 |
100 |
0.76 |
| ccpA | Lactococcus lactis subsp. lactis strain DGCC12653 |
55.589 |
99.399 |
0.553 |