Detailed information
Bioinformatically predicted
Overview
| Name | ccpA | Type | Regulator |
| Locus tag | MGCS36044_RS02990 | Genome accession | NZ_CP117287 |
| Coordinates | 552856..553857 (+) | Length | 333 a.a. |
| NCBI ID | WP_003049927.1 | Uniprot ID | A0A9X5LWR8 |
| Organism | Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 476065..556071 | 552856..553857 | within | 0 |
Gene organization within MGE regions
Location: 476065..556071
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MGCS36044_RS02560 (MGCS36044_01028) | metG | 476282..478279 (+) | 1998 | WP_049520067.1 | methionine--tRNA ligase | - |
| MGCS36044_RS02565 (MGCS36044_01030) | nrdF | 478812..479825 (+) | 1014 | WP_003055629.1 | class 1b ribonucleoside-diphosphate reductase subunit beta | - |
| MGCS36044_RS02570 (MGCS36044_01032) | nrdI | 479829..480302 (+) | 474 | WP_003055616.1 | class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI | - |
| MGCS36044_RS02575 (MGCS36044_01034) | nrdE | 480286..482472 (+) | 2187 | WP_003055626.1 | class 1b ribonucleoside-diphosphate reductase subunit alpha | - |
| MGCS36044_RS02580 (MGCS36044_01036) | brnQ | 482770..484104 (+) | 1335 | WP_003055639.1 | branched-chain amino acid transport system II carrier protein | - |
| MGCS36044_RS02585 (MGCS36044_01040) | - | 484503..484856 (+) | 354 | WP_084916410.1 | hypothetical protein | - |
| MGCS36044_RS02590 (MGCS36044_01042) | - | 485167..485403 (+) | 237 | WP_032460623.1 | DUF2829 domain-containing protein | - |
| MGCS36044_RS02595 (MGCS36044_01044) | - | 485396..486094 (+) | 699 | WP_003054338.1 | 3-oxoacyl-ACP reductase | - |
| MGCS36044_RS02600 (MGCS36044_01046) | - | 486091..486333 (+) | 243 | WP_042357856.1 | DUF3977 family protein | - |
| MGCS36044_RS02605 (MGCS36044_01048) | - | 486351..486800 (+) | 450 | WP_084916411.1 | ASCH domain-containing protein | - |
| MGCS36044_RS02610 (MGCS36044_01050) | - | 486802..487761 (+) | 960 | WP_003054341.1 | Gfo/Idh/MocA family protein | - |
| MGCS36044_RS02615 (MGCS36044_01052) | - | 488095..489432 (+) | 1338 | WP_046159276.1 | MFS transporter | - |
| MGCS36044_RS02620 (MGCS36044_01054) | glmU | 489604..490986 (+) | 1383 | WP_084916412.1 | bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU | - |
| MGCS36044_RS02625 (MGCS36044_01056) | - | 491017..491571 (+) | 555 | WP_003059987.1 | NUDIX domain-containing protein | - |
| MGCS36044_RS02630 (MGCS36044_01058) | macP | 491572..491823 (+) | 252 | WP_003054365.1 | cell wall synthase accessory phosphoprotein MacP | - |
| MGCS36044_RS02635 (MGCS36044_01060) | - | 491841..492536 (+) | 696 | WP_003054376.1 | 5'-methylthioadenosine/adenosylhomocysteine nucleosidase | - |
| MGCS36044_RS02640 (MGCS36044_01062) | - | 492609..493256 (-) | 648 | WP_003059888.1 | metal-dependent transcriptional regulator | - |
| MGCS36044_RS02645 (MGCS36044_01066) | - | 493402..494334 (+) | 933 | WP_003062287.1 | metal ABC transporter substrate-binding protein | - |
| MGCS36044_RS02650 (MGCS36044_01068) | - | 494399..495124 (+) | 726 | WP_003054363.1 | metal ABC transporter ATP-binding protein | - |
| MGCS36044_RS02655 (MGCS36044_01070) | - | 495125..495973 (+) | 849 | WP_003054335.1 | metal ABC transporter permease | - |
| MGCS36044_RS02660 (MGCS36044_01072) | - | 496104..496910 (-) | 807 | WP_003054349.1 | peptidylprolyl isomerase | - |
| MGCS36044_RS02665 (MGCS36044_01074) | - | 497128..499536 (+) | 2409 | WP_037590009.1 | DNA translocase FtsK | - |
| MGCS36044_RS02670 (MGCS36044_01076) | - | 499605..499958 (-) | 354 | WP_037587264.1 | DUF3397 domain-containing protein | - |
| MGCS36044_RS02675 (MGCS36044_01078) | rplK | 500201..500626 (+) | 426 | WP_003049875.1 | 50S ribosomal protein L11 | - |
| MGCS36044_RS02680 (MGCS36044_01080) | rplA | 500732..501421 (+) | 690 | WP_003049876.1 | 50S ribosomal protein L1 | - |
| MGCS36044_RS02685 | - | 501696..501830 (-) | 135 | WP_003054384.1 | hypothetical protein | - |
| MGCS36044_RS02690 (MGCS36044_01082) | - | 501924..502091 (-) | 168 | WP_003054374.1 | hypothetical protein | - |
| MGCS36044_RS02695 (MGCS36044_01084) | pyrH | 502373..503101 (+) | 729 | WP_003049878.1 | UMP kinase | - |
| MGCS36044_RS02700 (MGCS36044_01086) | frr | 503130..503687 (+) | 558 | WP_003054381.1 | ribosome recycling factor | - |
| MGCS36044_RS02705 (MGCS36044_01088) | - | 503796..504653 (+) | 858 | WP_003054345.1 | CvfB family protein | - |
| MGCS36044_RS02710 (MGCS36044_01090) | msrA | 504726..505235 (+) | 510 | WP_003054395.1 | peptide-methionine (S)-S-oxide reductase MsrA | - |
| MGCS36044_RS02715 (MGCS36044_01092) | - | 505232..505447 (+) | 216 | WP_003054340.1 | YozE family protein | - |
| MGCS36044_RS02720 (MGCS36044_01094) | - | 505607..506842 (+) | 1236 | WP_003054361.1 | LysM peptidoglycan-binding domain-containing protein | - |
| MGCS36044_RS02725 (MGCS36044_01096) | - | 507153..508925 (+) | 1773 | WP_003054339.1 | oleate hydratase | - |
| MGCS36044_RS02730 (MGCS36044_01098) | - | 509086..510147 (+) | 1062 | WP_003054347.1 | PhoH family protein | - |
| MGCS36044_RS02735 (MGCS36044_01100) | - | 510194..510769 (+) | 576 | WP_003054351.1 | uracil-DNA glycosylase family protein | - |
| MGCS36044_RS02740 (MGCS36044_01102) | ybeY | 510928..511425 (+) | 498 | WP_003054373.1 | rRNA maturation RNase YbeY | - |
| MGCS36044_RS02745 (MGCS36044_01104) | - | 511406..511813 (+) | 408 | WP_003054389.1 | diacylglycerol kinase family protein | - |
| MGCS36044_RS02750 (MGCS36044_01106) | era | 511934..512830 (+) | 897 | WP_002985743.1 | GTPase Era | - |
| MGCS36044_RS02755 (MGCS36044_01108) | - | 512851..513327 (+) | 477 | WP_002993018.1 | NUDIX hydrolase | - |
| MGCS36044_RS02760 (MGCS36044_01110) | - | 513636..513887 (-) | 252 | WP_080589767.1 | hypothetical protein | - |
| MGCS36044_RS02765 | - | 514188..514406 (+) | 219 | WP_072135532.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| MGCS36044_RS02770 (MGCS36044_01114) | - | 514603..516400 (-) | 1798 | Protein_489 | peptide cleavage/export ABC transporter | - |
| MGCS36044_RS02775 (MGCS36044_01116) | - | 516698..516925 (+) | 228 | WP_022554332.1 | Blp family class II bacteriocin | - |
| MGCS36044_RS02780 (MGCS36044_01118) | - | 516974..517291 (+) | 318 | WP_002994587.1 | hypothetical protein | - |
| MGCS36044_RS02785 (MGCS36044_01120) | - | 517411..518495 (+) | 1085 | Protein_492 | IS3 family transposase | - |
| MGCS36044_RS02790 (MGCS36044_01122) | - | 518709..520127 (+) | 1419 | WP_275902596.1 | IS1182 family transposase | - |
| MGCS36044_RS02800 (MGCS36044_01126) | comE/blpR | 521748..522497 (+) | 750 | WP_030126108.1 | response regulator transcription factor | Regulator |
| MGCS36044_RS02810 (MGCS36044_01130) | - | 522839..523972 (-) | 1134 | WP_275902597.1 | ISAs1-like element IS1548 family transposase | - |
| MGCS36044_RS02815 (MGCS36044_01132) | - | 524202..525158 (+) | 957 | WP_046166194.1 | sensor histidine kinase | - |
| MGCS36044_RS02820 (MGCS36044_01134) | - | 525306..525431 (-) | 126 | WP_011017462.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | - |
| MGCS36044_RS02825 (MGCS36044_01138) | - | 525508..526872 (-) | 1365 | WP_084916305.1 | bacteriocin secretion accessory protein | - |
| MGCS36044_RS02830 (MGCS36044_01140) | comA/nlmT | 526883..529036 (-) | 2154 | WP_084916306.1 | peptide cleavage/export ABC transporter | Regulator |
| MGCS36044_RS02835 (MGCS36044_01142) | - | 529323..529550 (+) | 228 | WP_002992018.1 | Blp family class II bacteriocin | - |
| MGCS36044_RS02840 (MGCS36044_01144) | - | 529563..529763 (+) | 201 | WP_003060803.1 | class IIb bacteriocin, lactobin A/cerein 7B family | - |
| MGCS36044_RS02845 (MGCS36044_01146) | - | 530057..530251 (+) | 195 | WP_002990768.1 | hypothetical protein | - |
| MGCS36044_RS02850 (MGCS36044_01148) | - | 530299..530580 (+) | 282 | WP_011054252.1 | hypothetical protein | - |
| MGCS36044_RS02855 (MGCS36044_01150) | - | 530774..531184 (+) | 411 | WP_003061293.1 | hypothetical protein | - |
| MGCS36044_RS02860 | - | 531431..531678 (+) | 248 | Protein_506 | hypothetical protein | - |
| MGCS36044_RS02865 (MGCS36044_01152) | - | 531700..531954 (+) | 255 | WP_014612089.1 | CPBP family intramembrane glutamic endopeptidase | - |
| MGCS36044_RS02870 (MGCS36044_01156) | - | 532366..533103 (+) | 738 | WP_228113938.1 | hypothetical protein | - |
| MGCS36044_RS02875 (MGCS36044_01158) | - | 533253..534179 (-) | 927 | Protein_509 | hypothetical protein | - |
| MGCS36044_RS02880 | shp2 | 534264..534332 (-) | 69 | WP_134771781.1 | peptide pheromone SHP2 | - |
| MGCS36044_RS02885 (MGCS36044_01160) | rgg2 | 534422..535276 (+) | 855 | Protein_511 | quorum-sensing system transcriptional regulator Rgg2 | - |
| MGCS36044_RS02890 (MGCS36044_01162) | mutM | 535458..536285 (+) | 828 | WP_084916308.1 | DNA-formamidopyrimidine glycosylase | - |
| MGCS36044_RS02895 (MGCS36044_01164) | coaE | 536264..536875 (+) | 612 | WP_172453883.1 | dephospho-CoA kinase | - |
| MGCS36044_RS02900 | - | 536890..537123 (-) | 234 | WP_159335598.1 | hypothetical protein | - |
| MGCS36044_RS02905 (MGCS36044_01166) | - | 537243..537944 (+) | 702 | WP_003056868.1 | ATP-binding cassette domain-containing protein | - |
| MGCS36044_RS02910 (MGCS36044_01168) | - | 537934..539571 (+) | 1638 | WP_022554345.1 | hypothetical protein | - |
| MGCS36044_RS02915 (MGCS36044_01170) | - | 539681..541183 (+) | 1503 | WP_084916309.1 | helicase HerA-like domain-containing protein | - |
| MGCS36044_RS02920 (MGCS36044_01172) | - | 541362..542564 (+) | 1203 | WP_080147973.1 | multidrug efflux MFS transporter | - |
| MGCS36044_RS02925 | rpmG | 542561..542707 (+) | 147 | WP_003047126.1 | 50S ribosomal protein L33 | - |
| MGCS36044_RS02930 (MGCS36044_01174) | secG | 542753..542989 (+) | 237 | WP_003047129.1 | preprotein translocase subunit SecG | - |
| MGCS36044_RS02935 (MGCS36044_01176) | rnr | 543086..545416 (+) | 2331 | WP_084916311.1 | ribonuclease R | - |
| MGCS36044_RS02940 (MGCS36044_01178) | smpB | 545419..545886 (+) | 468 | WP_022554349.1 | SsrA-binding protein SmpB | - |
| MGCS36044_RS02945 (MGCS36044_01180) | - | 546065..546421 (+) | 357 | WP_003053910.1 | hypothetical protein | - |
| MGCS36044_RS02950 (MGCS36044_01182) | - | 546514..547862 (+) | 1349 | WP_111678974.1 | IS3 family transposase | - |
| MGCS36044_RS02955 (MGCS36044_01184) | - | 547919..548845 (-) | 927 | WP_003053920.1 | glycosyltransferase family 2 protein | - |
| MGCS36044_RS10620 (MGCS36044_01186) | - | 548982..550166 (-) | 1185 | Protein_526 | DNA/RNA non-specific endonuclease | - |
| MGCS36044_RS02975 (MGCS36044_01188) | - | 550504..550878 (-) | 375 | WP_046177445.1 | VOC family protein | - |
| MGCS36044_RS02980 (MGCS36044_01190) | - | 550888..551553 (-) | 666 | WP_003058626.1 | NAD(P)H-dependent oxidoreductase | - |
| MGCS36044_RS02985 (MGCS36044_01192) | - | 551597..552682 (-) | 1086 | WP_003058632.1 | M24 family metallopeptidase | - |
| MGCS36044_RS02990 (MGCS36044_01194) | ccpA | 552856..553857 (+) | 1002 | WP_003049927.1 | catabolite control protein A | Regulator |
| MGCS36044_RS02995 (MGCS36044_01196) | - | 554011..555474 (+) | 1464 | WP_012766666.1 | alpha-amylase | - |
Sequence
Protein
Download Length: 333 a.a. Molecular weight: 36683.74 Da Isoelectric Point: 5.7248
>NTDB_id=783320 MGCS36044_RS02990 WP_003049927.1 552856..553857(+) (ccpA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPIVLAGTVDLDHQLPS
VNIDYKAAVSNVVDILAENHQSIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPIVLAGTVDLDHQLPS
VNIDYKAAVSNVVDILAENHQSIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK
Nucleotide
Download Length: 1002 bp
>NTDB_id=783320 MGCS36044_RS02990 WP_003049927.1 552856..553857(+) (ccpA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044]
ATGAATACAGATGATACCATCACGATTTATGACGTTGCCCGTGAAGCTGGTGTTTCTATGGCAACTGTTAGTCGTGTTGT
TAATGGCAATAAAAACGTTAAGGAAAACACGCGTAAGAAAGTTTTAGAAGTCATTGACCGCCTAGATTATCGTCCAAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAAACAACAACCGTCGGGGTTGTGATTCCGAATATTGCAAACAGTTATTTTTCT
ATTTTAGCCAAAGGTATTGATGATATCGCCGCTATGTATAAATATAATATTGTACTTGCCTCTAGTGATGAGGATGATGA
CAAGGAGGTTAACGTTGTTAATACCCTCTTTGCTAAGCAAGTTGACGGTATTATCTTTATGGGGCACCACTTGACTGAAA
AAATCCGTGCGGAATTTTCACGCTCACGCACCCCGATTGTTTTAGCAGGGACAGTTGACCTTGATCATCAATTACCAAGT
GTTAATATTGACTATAAGGCAGCTGTGTCTAATGTGGTTGATATTTTGGCAGAAAACCATCAGAGCATTGCCTTTGTGTC
AGGACCACTTATTGATGACATCAATGGTAAAGTACGTTTGGCGGGTTACAAAGAAGGCTTGAAGCACAACAAACTTGACT
TCAAAGAAGGACTTGTTTTTGAAGCTAACTATTCTTATAAAGAAGGTTTTGAATTGGCACAACGTGTGATTAACTCAGGA
GCAACAGCAGCTTATGTGGCTGAAGATGAGTTAGCAGCGGGTCTTTTAAATGGTTTGTTTGAAGCAGGCAAACGCGTTCC
AGAAGATTTTGAAATCATCACAAGCAATGATTCACCAGTTGTTCAATATACCCGTCCAAACTTGAGTTCTATCAGCCAAC
CCGTTTACGACTTGGGAGCTGTCAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGCGGAACCACTAAATAG
ATGAATACAGATGATACCATCACGATTTATGACGTTGCCCGTGAAGCTGGTGTTTCTATGGCAACTGTTAGTCGTGTTGT
TAATGGCAATAAAAACGTTAAGGAAAACACGCGTAAGAAAGTTTTAGAAGTCATTGACCGCCTAGATTATCGTCCAAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAAACAACAACCGTCGGGGTTGTGATTCCGAATATTGCAAACAGTTATTTTTCT
ATTTTAGCCAAAGGTATTGATGATATCGCCGCTATGTATAAATATAATATTGTACTTGCCTCTAGTGATGAGGATGATGA
CAAGGAGGTTAACGTTGTTAATACCCTCTTTGCTAAGCAAGTTGACGGTATTATCTTTATGGGGCACCACTTGACTGAAA
AAATCCGTGCGGAATTTTCACGCTCACGCACCCCGATTGTTTTAGCAGGGACAGTTGACCTTGATCATCAATTACCAAGT
GTTAATATTGACTATAAGGCAGCTGTGTCTAATGTGGTTGATATTTTGGCAGAAAACCATCAGAGCATTGCCTTTGTGTC
AGGACCACTTATTGATGACATCAATGGTAAAGTACGTTTGGCGGGTTACAAAGAAGGCTTGAAGCACAACAAACTTGACT
TCAAAGAAGGACTTGTTTTTGAAGCTAACTATTCTTATAAAGAAGGTTTTGAATTGGCACAACGTGTGATTAACTCAGGA
GCAACAGCAGCTTATGTGGCTGAAGATGAGTTAGCAGCGGGTCTTTTAAATGGTTTGTTTGAAGCAGGCAAACGCGTTCC
AGAAGATTTTGAAATCATCACAAGCAATGATTCACCAGTTGTTCAATATACCCGTCCAAACTTGAGTTCTATCAGCCAAC
CCGTTTACGACTTGGGAGCTGTCAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGCGGAACCACTAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccpA | Streptococcus gordonii str. Challis substr. CH1 |
77.778 |
100 |
0.778 |
| ccpA | Streptococcus pneumoniae D39 |
75.976 |
100 |
0.76 |
| ccpA | Lactococcus lactis subsp. lactis strain DGCC12653 |
55.589 |
99.399 |
0.553 |