Detailed information NTG0781712

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: M0P28_RS11080
• Genome accession: NZ_CP116958
• Coordinates: 2181890..2182621 (-)
• Length: 243 a.a.
• NCBI ID: WP_117480045.1
• Uniprot ID: -
• Organism: Streptococcus pasteurianus strain WUSP074
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2176890..2187621

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M0P28_RS11060 (M0P28_11060)	-	2177803..2178114 (-)	312	WP_003066564.1	bacteriocin immunity protein	-
M0P28_RS11065 (M0P28_11065)	-	2178976..2180136 (-)	1161	WP_117480154.1	IS110 family transposase	-
M0P28_RS11070 (M0P28_11070)	-	2180416..2180553 (+)	138	WP_003066566.1	hypothetical protein	-
M0P28_RS11075 (M0P28_11075)	-	2180575..2181882 (-)	1308	WP_117480042.1	sensor histidine kinase	-
M0P28_RS11080 (M0P28_11080)	comE/comE1	2181890..2182621 (-)	732	WP_117480045.1	response regulator transcription factor	Regulator
M0P28_RS11085 (M0P28_11085)	-	2182638..2182922 (-)	285	WP_003066573.1	LytTR family DNA-binding domain-containing protein	-
M0P28_RS11090 (M0P28_11090)	-	2183619..2184632 (-)	1014	WP_003066577.1	hypothetical protein	-
M0P28_RS11095 (M0P28_11095)	-	2184804..2185100 (-)	297	WP_003066579.1	bacteriocin immunity protein	-
M0P28_RS11100 (M0P28_11100)	-	2185100..2185318 (-)	219	WP_003066580.1	Blp family class II bacteriocin	-
M0P28_RS12200 (M0P28_11105)	-	2185511..2185630 (-)	120	WP_253066439.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
M0P28_RS11110 (M0P28_11110)	-	2185627..2185974 (-)	348	WP_003066582.1	CPBP family intramembrane glutamic endopeptidase	-
M0P28_RS11115 (M0P28_11115)	-	2186004..2186183 (-)	180	WP_003066584.1	hypothetical protein	-
M0P28_RS11120 (M0P28_11120)	-	2186354..2186665 (-)	312	WP_248488375.1	hypothetical protein	-
M0P28_RS11125 (M0P28_11125)	-	2186754..2186984 (-)	231	WP_003066588.1	bacteriocin	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28418.46 Da
• Isoelectric Point: 5.2357

>NTDB_id=781712 M0P28_RS11080 WP_117480045.1 2181890..2182621(-) (comE/comE1) [Streptococcus pasteurianus strain WUSP074]
MLDIYVLEDNIIQQFRMEREIATIMAKNNWDYQRIEVFSSANEIIAKATEKGEHQIFFLDLEIRDDEKQGIDVAKAIREQ
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQAFSERIELCLKEAMKHQNDNFGENSFLFETPKARVRVLYSDIL
YFETSPAVHRVILHTRNERVEFYATIAEIAKSDKRLFKCHRSFIINVDNVVRFDKATRSVYFETGDSCLVSRDKIKPLLN
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=781712 M0P28_RS11080 WP_117480045.1 2181890..2182621(-) (comE/comE1) [Streptococcus pasteurianus strain WUSP074]
ATGTTAGATATTTATGTACTAGAGGATAATATCATACAGCAATTTCGTATGGAACGCGAGATTGCGACCATTATGGCAAA
AAATAATTGGGACTATCAGAGAATAGAGGTGTTTAGTTCCGCAAATGAGATTATAGCTAAGGCAACTGAAAAAGGAGAGC
ATCAAATTTTCTTTCTTGATTTAGAAATCAGAGACGACGAAAAACAAGGAATTGATGTCGCTAAAGCCATTCGTGAACAA
GATGCAACGGCTATCATTGTTTTTGTAACAACCCATTCAGAATTTATGCTGCTGACTTACCAAGCGTTAGTAGGGGCGAT
TGATTTTATTGATAAGAACCTGAATGACCAAGCATTTAGTGAACGCATAGAGTTGTGCCTAAAGGAAGCCATGAAACATC
AAAATGATAATTTCGGCGAGAATTCCTTTTTGTTTGAAACTCCTAAAGCACGTGTGCGCGTTCTATATAGTGACATTCTT
TATTTCGAAACATCTCCTGCCGTGCACCGTGTGATTTTGCATACGAGAAATGAAAGAGTGGAATTTTATGCGACGATTGC
AGAGATTGCTAAATCAGACAAACGTCTTTTCAAGTGTCACCGTTCTTTTATCATTAATGTGGATAATGTGGTCAGATTTG
ATAAAGCGACACGAAGTGTTTATTTCGAAACTGGGGACTCTTGCTTAGTTTCGAGGGATAAAATAAAACCTCTATTGAAT
GAGATGAGGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-238)

• Response regulator receiver domain (Response_reg) (11-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	71.605	100	0.716
comE/blpR	Streptococcus mutans UA159	48.954	98.354	0.481
comE/comE2	Streptococcus equinus JB1	45.868	99.588	0.457