Detailed information NTG0781702

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: M0P28_RS08590
• Genome accession: NZ_CP116958
• Coordinates: 1690101..1691453 (-)
• Length: 450 a.a.
• NCBI ID: WP_013852111.1
• Uniprot ID: A0AAW6YHW1
• Organism: Streptococcus pasteurianus strain WUSP074
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1688057..1689157	1690101..1691453	flank	944

Gene organization within MGE regions

Location: 1688057..1691453

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M0P28_RS08580 (M0P28_08580)	-	1688102..1689157 (-)	1056	Protein_1637	IS1182 family transposase	-
M0P28_RS08585 (M0P28_08585)	vicX	1689291..1690100 (-)	810	WP_117479415.1	MBL fold metallo-hydrolase	Regulator
M0P28_RS08590 (M0P28_08590)	vicK	1690101..1691453 (-)	1353	WP_013852111.1	cell wall metabolism sensor histidine kinase VicK	Regulator

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51389.45 Da
• Isoelectric Point: 4.6855

>NTDB_id=781702 M0P28_RS08590 WP_013852111.1 1690101..1691453(-) (vicK) [Streptococcus pasteurianus strain WUSP074]
MNDTMLQNLTYFEQAILFLLAFVAVYFVYLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELADQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRAGNITMINQTALQQLNLEQEEALQMNIVDILGADSTYSYHDLVSKTPE
IVLNRRDGTGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTISGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSEIYDEWEDEEE

Nucleotide

• Length: 1353 bp

>NTDB_id=781702 M0P28_RS08590 WP_013852111.1 1690101..1691453(-) (vicK) [Streptococcus pasteurianus strain WUSP074]
ATGAATGATACAATGTTACAAAATTTAACTTATTTTGAACAAGCCATTCTCTTTCTTTTAGCATTTGTCGCAGTTTATTT
TGTTTATTTAGCGATAAGAGATTATCGAACTTCTGTTAATATTCGACGTTTGAGTGGTAAAGTGCGAGAGCTTATCACAG
GAAAATATACAGAAGATATTATTATTGAAAAAGATAGAGACTTAGCTGAGTTAGCTGACCAATTAAATGATTTGTCAACA
GTCTTTCGTTTAGCACAGGAAAATTTGGCGCAAGAAAAGAATCGTTTAGCAAGTATCTTATCCTATATGACAGACGGTGT
CTTGGCGACTGACCGTGCTGGAAATATCACAATGATTAATCAAACCGCGCTACAACAACTCAATTTAGAGCAAGAAGAAG
CTTTGCAGATGAATATTGTTGATATTTTAGGAGCTGATAGTACTTATAGTTATCATGATTTGGTGTCAAAAACACCTGAA
ATTGTCTTGAACCGTCGTGACGGAACAGGTGAATTTATTACTTTACGTATTCGATTTGCTCTAAATCGTCGTGATAGTGG
CTTTATTTCAGGGTTGATTGCTGTTTTGCATGACACAACCGAACAAGAAAAAGAAGACCGTGAGCGTCGCCTTTTCGTTT
CTAATGTTAGTCATGAATTGCGAACACCATTAACATCTGTAAAATCTTATCTGGAAGCTTTAGATGAAGGGGCACTCAAA
GAAGACATTGCGCCAAGCTTTATCAAAGTGTCTTTAGATGAAACAAACCGTATGATTCGTATGATTTCAGACTTACTTAA
TTTATCGCGTATTGATAATCAGACGGTTCAACTGGAAGTGGAAATGACCAATTTCACAGCTTTTATGACATCAATTCTTA
ACCGTTTTGATCAAATTAAAAGCCAACATACAATCAGTGGAAAACAGTATGAGATTGTCAGGGATTATCCGATTAAATCA
ATCTGGCTTGAAATTGATCCTGATAAGATGACGCAAGTTTTGGATAATATCCTTAATAATGCTATCAAATATTCACCAGA
TGGTGGAAAAATCACAGTTAGCATGAAAACGACGGAAACACAGTTGATTATCTCAATCTCTGATGAAGGGCTTGGTATTC
CTAAGAAAGATTTGCCATTGATTTTCGACCGTTTCTATCGTGTGGATAAGGCTCGAAGTCGTGCCCAAGGTGGTTCAGGA
CTCGGCTTAGCTATCGCAAAAGAAATTGTCAAACAACATAAAGGTTTTATTTGGGCACAAAGTACTTACGGAAAAGGGTC
GACCTTTACAATTGTACTTCCTTACGAAAAAGATTCTGAAATTTATGATGAATGGGAGGATGAAGAAGAGTAG

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• PAS fold (PAS) (95-189)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	74.94	92.222	0.691
micB	Streptococcus pneumoniae Cp1015	66.038	94.222	0.622