Detailed information NTG0781246

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: QZH48_RS11995
• Genome accession: NZ_CP129879
• Coordinates: 2443019..2445541 (-)
• Length: 840 a.a.
• NCBI ID: WP_038602495.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain CAB701
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2438019..2450541

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QZH48_RS11975 (QZH48_11975)	ruvB	2438277..2439278 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
QZH48_RS11980 (QZH48_11980)	ruvA	2439405..2439998 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
QZH48_RS11985 (QZH48_11985)	hexB	2440110..2442080 (-)	1971	WP_146978291.1	DNA mismatch repair endonuclease MutL	Machinery gene
QZH48_RS11990 (QZH48_11990)	-	2442209..2442904 (-)	696	WP_038602492.1	hypothetical protein	-
QZH48_RS11995 (QZH48_11995)	hexA	2443019..2445541 (-)	2523	WP_038602495.1	DNA mismatch repair protein MutS	Machinery gene
QZH48_RS12000 (QZH48_12000)	-	2445734..2446081 (-)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
QZH48_RS12005 (QZH48_12005)	-	2446422..2446730 (-)	309	WP_047207033.1	helix-turn-helix transcriptional regulator	-
QZH48_RS12010 (QZH48_12010)	-	2446860..2447174 (+)	315	WP_098394237.1	hypothetical protein	-
QZH48_RS12015 (QZH48_12015)	-	2447186..2447596 (+)	411	WP_260310655.1	DUF6591 domain-containing protein	-
QZH48_RS12020 (QZH48_12020)	-	2447640..2448521 (-)	882	WP_058206124.1	NAD(P)-dependent oxidoreductase	-
QZH48_RS12025 (QZH48_12025)	-	2448563..2448769 (-)	207	WP_003132002.1	hypothetical protein	-
QZH48_RS12035 (QZH48_12035)	-	2449001..2449378 (-)	378	WP_058206123.1	DUF1634 domain-containing protein	-
QZH48_RS12040 (QZH48_12040)	-	2449378..2450229 (-)	852	WP_038602517.1	sulfite exporter TauE/SafE family protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94163.09 Da
• Isoelectric Point: 4.6772

>NTDB_id=781246 QZH48_RS11995 WP_038602495.1 2443019..2445541(-) (hexA) [Lactococcus lactis subsp. lactis strain CAB701]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQLEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEDLRSQLDELPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIAKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRTETEQYIGRLQALAKAIAEIDCLQSLSVVAEKQGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALDHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFAENSSEIIEKIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=781246 QZH48_RS11995 WP_038602495.1 2443019..2445541(-) (hexA) [Lactococcus lactis subsp. lactis strain CAB701]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGTGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCTCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTCAAACGGGCAGTGACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCTTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTGGTA
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAGTTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAACTTGAAATTCCTGAAAATTTACTGATAGATTTGTCAGGATTGACCGCTTTAG
AAAATCAGGTCGCTTCAAAATTGTTGGCTTACGTAAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAAACGAAAACAGCGATGGGAACCCGAATGTTACGGTCGTGGATTG
ACCGTCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCTGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTGTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAACTGGCTAATTCTTTATCAAATGTTCCTGCTATCAAAAATATTTTGGGAATGCTTAACGAAGCTC
CGTTAGAAGATTTAAGAAGCCAATTAGACGAGCTTCCGGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGAACTTCTTGGATTGCAAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTAAGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGTTGAATAGTGTTCCTGAACATTTTTATCGGAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAGGCGCGTGAAAAATCATCTTC
TCTAGAATATGATTTATTCATGGGACTTCGGACTGAAACTGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAGCAA
TTGCTGAAATTGACTGTTTACAAAGTTTATCTGTCGTTGCCGAAAAACAAGGTTATATCCGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCAAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCCGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAGACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGATCATCTTGATAATGTCCATGTTGCTACTTTGGAACAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGGCCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTGCTGAAAACTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCATTGAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (124-237)

• MutS domain V (MutS_V) (598-784)

• MutS domain III (MutS_III) (254-544)

• MutS domain I (MutS_I) (7-116)

• MutS family domain IV (MutS_IV) (413-503)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.455	100	0.648
mutS	Pseudomonas stutzeri strain ATCC 17587	37.923	100	0.387