Detailed information NTG0781127

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: QZN16_RS08070
• Genome accession: NZ_CP129876
• Coordinates: 1594479..1596470 (-)
• Length: 663 a.a.
• NCBI ID: WP_000567072.1
• Uniprot ID: Q8DYL6
• Organism: Streptococcus agalactiae strain NEM316
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1589479..1601470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QZN16_RS08065	-	1592886..1594382 (+)	1497	WP_000571941.1	helix-turn-helix domain-containing protein	-
QZN16_RS08070	uvrB	1594479..1596470 (-)	1992	WP_000567072.1	excinuclease ABC subunit UvrB	Machinery gene
QZN16_RS08075	-	1596531..1597451 (-)	921	WP_001042316.1	CPBP family intramembrane glutamic endopeptidase	-
QZN16_RS08080	-	1597634..1599817 (+)	2184	WP_000681005.1	ABC transporter substrate-binding protein/permease	-
QZN16_RS08085	-	1599817..1600557 (+)	741	WP_000818887.1	amino acid ABC transporter ATP-binding protein	-
QZN16_RS08090	-	1600706..1601056 (+)	351	WP_000656279.1	hypothetical protein	-
QZN16_RS08095	-	1601148..1601306 (-)	159	WP_000502594.1	hypothetical protein	-

Sequence

Protein

• Length: 663 a.a.
• Molecular weight: 76016.94 Da
• Isoelectric Point: 4.6430

>NTDB_id=781127 QZN16_RS08070 WP_000567072.1 1594479..1596470(-) (uvrB) [Streptococcus agalactiae strain NEM316]
MIDRKDTNRFKLVSKYSPSGDQPQAIETLVDNIEGGEKAQILKGATGTGKTYTMSQVIAQVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGQEISRDQLLNNLVDIQFERNDIDFQRGKFRVRGDVVEVFPASRDEHAFRIEFFGDEIDRIREIESLTGRVL
GEVEHLAIFPATHFMTNDEHMEEAISKIQAEMENQVELFEKEGKLIEAQRIRQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTDTVVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRTEKGERTFITTLTKRMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSNGHVIMYADK
ITDSMQRAMDETARRRRLQMDYNEKHGIVPQTIKKEIRDLIAITKSNDSDKPEKVVDYSSLSKKERQAEIKALQQQMQEA
AELLDFELAAQIRDVILELKAID

Nucleotide

• Length: 1992 bp

>NTDB_id=781127 QZN16_RS08070 WP_000567072.1 1594479..1596470(-) (uvrB) [Streptococcus agalactiae strain NEM316]
ATGATAGATAGAAAAGATACTAACCGATTTAAATTAGTTTCCAAATATAGCCCTTCGGGAGATCAACCTCAAGCTATTGA
AACGTTGGTTGACAATATTGAAGGAGGAGAAAAAGCTCAGATTTTAAAAGGTGCTACTGGTACTGGTAAAACCTACACAA
TGAGCCAAGTTATCGCCCAAGTTAACAAGCCAACCTTGGTGATTGCACATAATAAAACCTTAGCAGGTCAACTTTATGGA
GAGTTTAAAGAATTTTTTCCTGACAATGCCGTAGAGTACTTTGTTTCATATTATGATTATTATCAACCAGAAGCTTATGT
GCCTTCTTCGGATACTTATATTGAAAAAGATAGTTCAGTCAATGACGAAATTGACAAATTACGTCACTCAGCGACTTCTT
CGTTATTAGAAAGAAATGACGTTATTGTTGTAGCATCTGTTTCTTGTATTTACGGTTTAGGTTCTCCTAAAGAGTATGCA
GACAGTGTTGTTAGCCTTAGGCCAGGTCAAGAAATTTCACGTGATCAGTTATTGAACAATCTCGTTGATATTCAATTTGA
GCGTAACGATATTGATTTTCAACGTGGAAAATTTCGCGTTCGTGGCGATGTTGTAGAAGTTTTTCCTGCGAGTCGTGATG
AGCATGCCTTTCGAATTGAATTTTTTGGTGATGAAATTGATCGTATAAGAGAAATAGAATCGTTAACAGGGCGTGTGCTA
GGAGAAGTGGAACATTTAGCTATTTTCCCAGCAACACACTTTATGACAAATGATGAACATATGGAAGAAGCTATTTCAAA
AATACAAGCTGAAATGGAAAATCAAGTAGAACTTTTTGAAAAAGAAGGGAAATTGATTGAAGCGCAACGTATTCGACAAA
GGACAGAATATGATATTGAAATGCTTCGTGAAATGGGATATACAAATGGTGTTGAGAACTACTCACGTCACATGGATGGT
AGAAGTGAAGGTGAGCCACCTTTTACTTTGTTAGATTTCTTCCCAGAAGATTTTTTGATTATGATTGATGAGAGTCACAT
GACAATGGGGCAAATCAAAGGGATGTATAATGGAGACCGTTCGCGTAAAGAAATGTTGGTTAATTACGGTTTCCGTTTAC
CATCTGCCTTAGATAACCGTCCACTTCGTCGTGAAGAATTCGAAAGCCATGTCCATCAAATTGTCTATGTATCTGCAACG
CCAGGAGACTATGAAATGGAGCAAACAGATACAGTTGTTGAGCAAATTATCCGGCCAACAGGACTTCTTGATCCAGAAGT
TGAAGTTAGACCAAGTATGGGGCAGATGGATGACTTGCTTGGTGAAATCAATTTGAGGACTGAAAAAGGTGAGCGTACCT
TTATTACAACATTGACAAAGCGTATGGCAGAAGACTTAACAGATTATCTCAAAGAAATGGGAGTTAAAGTTAAGTATATG
CACAGCGATATTAAAACCTTAGAACGTACAGAGATTATTCGTGATTTACGACTTGGTGTGTTTGATGTTTTAATTGGTAT
TAATCTCTTACGTGAAGGAATAGATGTTCCTGAGGTTTCCCTTGTTGCAATCTTAGATGCTGATAAGGAAGGTTTCCTTC
GTAATGAGCGTGGTCTTATCCAAACAATCGGACGTGCAGCACGTAACAGTAATGGTCATGTTATTATGTATGCTGATAAA
ATAACAGATTCTATGCAAAGAGCTATGGATGAAACCGCTCGCCGTCGTCGTTTACAAATGGATTATAATGAAAAGCATGG
AATTGTGCCACAAACAATTAAAAAAGAAATCCGTGATTTAATTGCTATTACTAAAAGTAATGACAGCGATAAGCCTGAAA
AAGTTGTCGATTACAGTAGTTTATCTAAAAAAGAAAGGCAAGCTGAAATTAAAGCTCTTCAACAGCAAATGCAAGAAGCA
GCTGAATTATTGGACTTTGAGCTAGCTGCACAAATCCGAGATGTTATCTTAGAACTAAAAGCAATCGATTAA

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• Helicase conserved C-terminal domain (Helicase_C) (446-549)

• UvrB/uvrC motif (UVR) (628-661)

• Type III restriction enzyme, res subunit (ResIII) (20-143)

• UvrB interaction domain (UvrB_inter) (164-254)

3D structure

• AlphaFold DB: Q8DYL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	87.179	100	0.872
uvrB	Streptococcus pneumoniae D39	87.179	100	0.872
uvrB	Streptococcus pneumoniae TIGR4	87.029	100	0.87