Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   MWM20_RS01870 Genome accession   NZ_AP025677
Coordinates   404386..405018 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain Rb-23     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 399386..410018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM20_RS01845 (TRECRb23_03620) yhfG 399507..399674 (+) 168 WP_000736858.1 YhfG family protein -
  MWM20_RS01850 (TRECRb23_03630) fic 399664..400266 (+) 603 WP_001280614.1 putative adenosine monophosphate-protein transferase Fic -
  MWM20_RS01855 (TRECRb23_03640) pabA 400298..400861 (+) 564 WP_000601888.1 aminodeoxychorismate synthase component 2 -
  MWM20_RS01860 (TRECRb23_03650) argD 400947..402167 (+) 1221 WP_000963780.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  MWM20_RS01865 (TRECRb23_03660) yhfK 402245..404335 (-) 2091 WP_001312144.1 YccS/YhfK family putative transporter -
  MWM20_RS01870 (TRECRb23_03670) crp 404386..405018 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  MWM20_RS01875 (TRECRb23_03680) yhfA 405320..405724 (+) 405 WP_001148908.1 OsmC family protein -
  MWM20_RS01880 (TRECRb23_03690) prkB 405779..406648 (-) 870 WP_001274684.1 phosphoribulokinase -
  MWM20_RS01885 (TRECRb23_03700) yheU 406702..406920 (-) 219 WP_000907085.1 YheU family protein -
  MWM20_RS01890 (TRECRb23_03710) yheT 406914..407936 (-) 1023 WP_000057389.1 hydrolase -
  MWM20_RS01895 (TRECRb23_03720) yheS 407936..409849 (-) 1914 WP_000634795.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=78097 MWM20_RS01870 WP_000242755.1 404386..405018(-) (crp) [Escherichia coli strain Rb-23]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=78097 MWM20_RS01870 WP_000242755.1 404386..405018(-) (crp) [Escherichia coli strain Rb-23]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGCCGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467