Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   MWM15_RS01835 Genome accession   NZ_AP025675
Coordinates   403330..403962 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain Rb-3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 398330..408962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM15_RS01810 (TRECRb3_03580) yhfG 398451..398618 (+) 168 WP_000736858.1 YhfG family protein -
  MWM15_RS01815 (TRECRb3_03590) fic 398608..399210 (+) 603 WP_001280615.1 putative adenosine monophosphate-protein transferase Fic -
  MWM15_RS01820 (TRECRb3_03600) pabA 399242..399805 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  MWM15_RS01825 (TRECRb3_03610) argD 399891..401111 (+) 1221 WP_000963809.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  MWM15_RS01830 (TRECRb3_03620) yhfK 401189..403279 (-) 2091 WP_001298205.1 YccS/YhfK family putative transporter -
  MWM15_RS01835 (TRECRb3_03630) crp 403330..403962 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  MWM15_RS01840 (TRECRb3_03640) yhfA 404264..404668 (+) 405 WP_001148908.1 OsmC family protein -
  MWM15_RS01845 (TRECRb3_03650) prkB 404723..405592 (-) 870 WP_001274680.1 phosphoribulokinase -
  MWM15_RS01850 (TRECRb3_03660) yheU 405646..405864 (-) 219 WP_000907085.1 YheU family protein -
  MWM15_RS01855 (TRECRb3_03670) yheT 405858..406880 (-) 1023 WP_000057389.1 hydrolase -
  MWM15_RS01860 (TRECRb3_03680) yheS 406880..408793 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=78009 MWM15_RS01835 WP_000242755.1 403330..403962(-) (crp) [Escherichia coli strain Rb-3]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=78009 MWM15_RS01835 WP_000242755.1 403330..403962(-) (crp) [Escherichia coli strain Rb-3]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment