Detailed information NTG0780021

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: PND17_RS00560
• Genome accession: NZ_CP116772
• Coordinates: 103137..104138 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain strain TSGB 4141
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 98137..109138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PND17_RS00540 (PND17_00540)	smpB	99242..99706 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
PND17_RS00545 (PND17_00545)	-	99860..101266 (+)	1407	WP_271298501.1	Cof-type HAD-IIB family hydrolase	-
PND17_RS00550 (PND17_00550)	-	101268..101633 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
PND17_RS00555 (PND17_00555)	-	101736..102821 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
PND17_RS00560 (PND17_00560)	ccpA	103137..104138 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
PND17_RS00565 (PND17_00565)	-	104197..104394 (+)	198	WP_011225705.1	hypothetical protein	-
PND17_RS00570 (PND17_00570)	-	104500..105264 (+)	765	WP_271298084.1	MmcQ/YjbR family DNA-binding protein	-
PND17_RS00575 (PND17_00575)	-	105279..106394 (+)	1116	WP_232973377.1	glycerate kinase	-
PND17_RS00580 (PND17_00580)	-	106441..106896 (-)	456	WP_232556841.1	YueI family protein	-
PND17_RS00585 (PND17_00585)	eno	107105..108409 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
PND17_RS00590 (PND17_00590)	-	108561..108746 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=780021 PND17_RS00560 WP_004197422.1 103137..104138(+) (ccpA) [Streptococcus thermophilus strain strain TSGB 4141]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=780021 PND17_RS00560 WP_004197422.1 103137..104138(+) (ccpA) [Streptococcus thermophilus strain strain TSGB 4141]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCGAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGTAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547