Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   MWM17_RS02025 Genome accession   NZ_AP025657
Coordinates   448113..448745 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain TUM13867     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 443113..453745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM17_RS02000 (TUM13867_03880) yhfG 443245..443412 (+) 168 WP_000736851.1 YhfG family protein -
  MWM17_RS02005 (TUM13867_03890) fic 443402..444004 (+) 603 WP_001280634.1 putative adenosine monophosphate-protein transferase Fic -
  MWM17_RS02010 (TUM13867_03900) pabA 444036..444599 (+) 564 WP_000601862.1 aminodeoxychorismate synthase component 2 -
  MWM17_RS02015 (TUM13867_03910) argD 444685..445905 (+) 1221 WP_000190012.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  MWM17_RS02020 (TUM13867_03920) yhfK 445972..448062 (-) 2091 WP_001309799.1 YccS/YhfK family putative transporter -
  MWM17_RS02025 (TUM13867_03930) crp 448113..448745 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  MWM17_RS02030 (TUM13867_03940) yhfA 449047..449451 (+) 405 WP_001148908.1 OsmC family protein -
  MWM17_RS02035 (TUM13867_03950) prkB 449506..450375 (-) 870 WP_001274680.1 phosphoribulokinase -
  MWM17_RS02040 (TUM13867_03960) yheU 450429..450647 (-) 219 WP_000907085.1 YheU family protein -
  MWM17_RS02045 (TUM13867_03970) yheT 450641..451663 (-) 1023 WP_000057395.1 hydrolase -
  MWM17_RS02050 (TUM13867_03980) yheS 451663..453576 (-) 1914 WP_000634840.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=77844 MWM17_RS02025 WP_000242755.1 448113..448745(-) (crp) [Escherichia coli strain TUM13867]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=77844 MWM17_RS02025 WP_000242755.1 448113..448745(-) (crp) [Escherichia coli strain TUM13867]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAGGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACTGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment