Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   QYH60_RS12575 Genome accession   NZ_CP129292
Coordinates   2540337..2542415 (-) Length   692 a.a.
NCBI ID   WP_023189444.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain KMGR2-43     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2535337..2547415
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYH60_RS12555 (QYH60_12555) fabI 2536648..2537400 (-) 753 WP_301401172.1 enoyl-ACP reductase FabI -
  QYH60_RS12560 (QYH60_12560) fabZ 2537676..2538131 (+) 456 WP_003130498.1 3-hydroxyacyl-ACP dehydratase FabZ -
  QYH60_RS12565 (QYH60_12565) - 2538199..2539317 (-) 1119 WP_012897289.1 M20 family metallopeptidase -
  QYH60_RS12570 (QYH60_12570) - 2539332..2540141 (-) 810 WP_301401174.1 ABC transporter substrate-binding protein -
  QYH60_RS12575 (QYH60_12575) uvrB 2540337..2542415 (-) 2079 WP_023189444.1 excinuclease ABC subunit UvrB Machinery gene
  QYH60_RS12580 (QYH60_12580) - 2542426..2542887 (-) 462 WP_308858979.1 RNA pyrophosphohydrolase -
  QYH60_RS12585 (QYH60_12585) def 2543035..2543670 (+) 636 WP_003130816.1 peptide deformylase -
  QYH60_RS12590 (QYH60_12590) gap 2543813..2544826 (-) 1014 WP_003130818.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  QYH60_RS12595 (QYH60_12595) - 2544999..2545469 (+) 471 WP_058208345.1 Rrf2 family transcriptional regulator -

Sequence

Protein


Download         Length: 692 a.a.        Molecular weight: 79103.41 Da        Isoelectric Point: 4.5652

>NTDB_id=778219 QYH60_RS12575 WP_023189444.1 2540337..2542415(-) (uvrB) [Lactococcus lactis subsp. lactis strain KMGR2-43]
MAIERITDNKFELVSKYEPAGDQGEAIAELVDNIENGEKAQILRGATGTGKTYTMSQVIARTGKPTLVMAHNKTLAGQLY
SEFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEY
QDSVVSLRPGQEISRDQLLNDLVGIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRIREIEVLTGQV
LGEVDHLAIFPATHFMTNDDRMEESIAKIEAELEEQLKVFRSEGKLLEAQRLEQRTNYDIEMLREMGYCNGVENYSRHMD
GREEGEPPYTLLDFFPDDFMIMIDESHMTMGQVKGMYNGDRARKEMLCNYGFRLPSALDNRPLKREEFESHVHQIVYVSA
TPGDYEMEQTDTIVEQIIRPTGLLDPVVEVRPMMGQIDDLVGEIHKRAEKNERVFVTTLTKKMSEDLTAYFKEMGIKVKY
MHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVILYSD
MAKALDENDPADKEILDSGYYTEYEGQKYKITRSMKHAMDETARRREIQMAYNEEHGITPQTIKKEIRDLIAITKKTDSG
EIEEVDASAMTKKERKALVKKLEKEMQQAASALDFEGAAQLRDMVLELRAMD

Nucleotide


Download         Length: 2079 bp        

>NTDB_id=778219 QYH60_RS12575 WP_023189444.1 2540337..2542415(-) (uvrB) [Lactococcus lactis subsp. lactis strain KMGR2-43]
ATGGCTATAGAAAGAATAACAGATAATAAATTTGAACTTGTTTCAAAATATGAGCCAGCCGGTGACCAAGGTGAGGCGAT
TGCTGAGTTAGTAGATAATATTGAGAATGGGGAAAAAGCTCAAATTTTACGTGGAGCAACAGGAACAGGGAAAACTTACA
CCATGAGTCAAGTGATTGCACGGACAGGTAAACCTACTCTTGTTATGGCTCATAATAAAACACTGGCTGGTCAATTATAC
AGTGAATTTAAAGAGTTTTTTCCAAATAATGCAGTCGAGTATTTCGTATCCTACTATGATTATTATCAACCCGAAGCCTA
TGTTCCAAGTTCTGACACCTATATTGAAAAAGACAGTTCGGTCAATGATGAAATTGATAAATTGCGTCATAGTGCGACCT
CAAGCTTATTGGAACGTAATGATGTGATTGTTGTGGCCTCAGTTTCTTGTATTTATGGTTTGGGTTCACCCAAAGAGTAT
CAAGATTCGGTGGTTTCATTGCGCCCAGGTCAAGAAATTTCTCGTGACCAACTTTTAAATGATTTGGTAGGAATTCAATT
TGAGCGAAATGATATTGACTTTCAACGGGGCTGTTTCCGAGTTCGTGGGGATGTTGTAGAAGTTTTTCCAGCCTCTCGTG
ATGAACATGCCTTTCGTGTTGAATTTTTCGGTGATGAAATTGACCGTATCCGTGAAATTGAAGTTTTGACCGGACAAGTT
TTAGGTGAAGTAGACCATTTGGCAATTTTTCCAGCGACACATTTCATGACAAATGATGACCGTATGGAAGAATCAATTGC
CAAGATAGAAGCAGAATTAGAAGAACAACTAAAAGTTTTCCGCTCAGAAGGAAAACTTCTTGAGGCTCAACGTTTAGAAC
AAAGAACCAACTACGATATCGAAATGCTCCGTGAAATGGGTTATTGTAATGGTGTTGAAAACTATTCACGTCATATGGAT
GGGCGCGAGGAAGGCGAACCTCCGTATACTTTGCTTGATTTCTTTCCTGATGATTTCATGATTATGATTGATGAATCACA
CATGACAATGGGGCAAGTAAAAGGAATGTATAACGGTGACAGAGCCCGTAAAGAAATGCTTTGTAATTATGGATTCCGCC
TGCCTTCAGCCCTCGATAACCGTCCTTTAAAAAGAGAAGAATTTGAAAGTCATGTGCATCAAATTGTTTATGTTTCAGCA
ACCCCTGGGGATTATGAGATGGAGCAGACCGATACCATTGTTGAACAAATTATTCGTCCAACAGGTCTATTAGATCCTGT
CGTAGAAGTTCGACCAATGATGGGACAAATCGATGATTTAGTTGGTGAAATTCATAAACGAGCTGAGAAAAACGAACGAG
TATTCGTCACGACTTTGACTAAAAAGATGTCAGAAGATTTAACTGCCTATTTCAAGGAAATGGGGATAAAAGTTAAATAT
ATGCACTCGGATATCAAAACATTAGAACGAACCGAAATTATTCGGGATTTGCGTTTAGGAGTCTTTGATGTTCTGGTGGG
AATAAATCTGCTTCGCGAAGGGATAGATGTGCCAGAAGTTTCTTTAGTCGCGATTTTGGATGCTGATAAAGAAGGATTTT
TACGTAATGAGCGTGGCTTGATTCAGACCATTGGTCGTGCAGCACGTAATAGTGAAGGCCATGTTATTCTTTATTCTGAT
ATGGCTAAAGCCCTTGATGAAAATGATCCTGCGGATAAAGAAATCTTAGATAGTGGTTATTATACAGAATACGAGGGTCA
AAAGTATAAAATAACGCGTTCAATGAAACATGCGATGGATGAAACAGCCCGTCGGCGTGAAATTCAAATGGCTTATAATG
AAGAACATGGAATCACACCTCAAACGATCAAAAAAGAAATTCGTGATTTGATTGCCATTACTAAGAAAACTGATTCTGGT
GAGATTGAAGAAGTTGATGCAAGTGCGATGACTAAGAAAGAACGTAAAGCATTAGTCAAAAAACTTGAAAAAGAAATGCA
ACAAGCGGCTAGCGCCCTCGACTTTGAAGGAGCTGCTCAGTTACGTGATATGGTATTAGAATTACGTGCAATGGATTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(165-255)

Helicase conserved C-terminal domain (Helicase_C)

(441-550)

Type III restriction enzyme, res subunit (ResIII)

(19-144)

Ultra-violet resistance protein B (UvrB)

(590-628)

UvrB/uvrC motif (UVR)

(657-690)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae D39

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae TIGR4

81.884

99.711

0.816