Detailed information NTG0778151

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: QYH60_RS03105
• Genome accession: NZ_CP129292
• Coordinates: 608204..610726 (+)
• Length: 840 a.a.
• NCBI ID: WP_301401280.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain KMGR2-43
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 603204..615726

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYH60_RS03070 (QYH60_03070)	-	604430..604609 (-)	180	WP_003132007.1	hypothetical protein	-
QYH60_RS03075 (QYH60_03075)	-	604795..605646 (+)	852	WP_021463283.1	sulfite exporter TauE/SafE family protein	-
QYH60_RS03080 (QYH60_03080)	-	605646..606023 (+)	378	WP_003132003.1	DUF1634 domain-containing protein	-
QYH60_RS03090 (QYH60_03090)	-	606318..606524 (+)	207	WP_003132002.1	hypothetical protein	-
QYH60_RS03095 (QYH60_03095)	-	606566..607447 (+)	882	WP_012898703.1	NAD(P)-dependent oxidoreductase	-
QYH60_RS03100 (QYH60_03100)	-	607663..608010 (+)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
QYH60_RS03105 (QYH60_03105)	hexA	608204..610726 (+)	2523	WP_301401280.1	DNA mismatch repair protein MutS	Machinery gene
QYH60_RS03110 (QYH60_03110)	-	610841..611536 (+)	696	WP_301401281.1	hypothetical protein	-
QYH60_RS03115 (QYH60_03115)	hexB	611665..613635 (+)	1971	WP_301401282.1	DNA mismatch repair endonuclease MutL	Machinery gene
QYH60_RS03120 (QYH60_03120)	ruvA	613748..614341 (+)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
QYH60_RS03125 (QYH60_03125)	ruvB	614468..615469 (+)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94237.21 Da
• Isoelectric Point: 4.6787

>NTDB_id=778151 QYH60_RS03105 WP_301401280.1 608204..610726(+) (hexA) [Lactococcus lactis subsp. lactis strain KMGR2-43]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQIEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEELKSQLDEIPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIAKLEADEKVKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRTETEQYIGRLQALAKTIAEIDCLQSLSVVAEKQGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALDHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFTENSSEIIEKIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=778151 QYH60_RS03105 WP_301401280.1 608204..610726(+) (hexA) [Lactococcus lactis subsp. lactis strain KMGR2-43]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGTGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCCCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTTAAACGGGCAGTAACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCCTATATGGACTTATCAACTGGTGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTAGTA
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAGTTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAAATTGAAATTCCTGAAAATTTACTGATAGATTTGTCAGGATTGACCGCCTTAG
AAAATCAAGTCGCTTCAAAATTGTTGGCTTATGTCAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAGACGAAAACAGCGATGGGAACCAGAATGTTACGGTCGTGGATTG
ACCGTCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCCGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTTTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAGCTGGCTAATTCTTTATCAAATGTTCCTGCTATCAAAAATATTTTGGGAATGCTTAATGAAGCTC
CATTAGAAGAGTTAAAAAGCCAATTAGACGAAATTCCAGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGGACTTCTTGGATTGCTAAATTGGAAGCAGATGAAAAAGTCAAGACAGGAATTTCCACACTACGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGTTGAATAGTGTTCCTGAACATTTTTATCGGAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCATC
TCTAGAATATGATTTATTCATGGGCCTTCGGACTGAAACGGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAACAA
TTGCTGAAATTGATTGTTTACAAAGTCTATCTGTCGTTGCCGAAAAACAAGGATATATCCGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCGAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCCGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAGACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGATCATCTTGATAATGTCCATGTTGCTACCTTGGAGCAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGACCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTACCGAAAATTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCATTGAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (254-544)

• MutS family domain IV (MutS_IV) (413-503)

• MutS domain I (MutS_I) (7-116)

• MutS domain II (MutS_II) (124-237)

• MutS domain V (MutS_V) (598-784)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.455	100	0.648
mutS	Pseudomonas stutzeri strain ATCC 17587	37.69	100	0.385