Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Machinery gene
Locus tag   BV187_RS02495 Genome accession   NZ_CP116490
Coordinates   512130..512543 (-) Length   137 a.a.
NCBI ID   WP_011272047.1    Uniprot ID   Q4QNA9
Organism   Haemophilus influenzae strain 93P10H1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 507130..517543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV187_RS02465 (BV187_0503) - 507515..507787 (-) 273 WP_105893545.1 HU family DNA-binding protein -
  BV187_RS02470 (BV187_0504) - 507925..508515 (-) 591 WP_105893546.1 YjaG family protein -
  BV187_RS02475 (BV187_0505) nudC 508551..509345 (-) 795 WP_105893547.1 NAD(+) diphosphatase -
  BV187_RS02480 (BV187_0506) nfuA 509412..510008 (-) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  BV187_RS02485 (BV187_0507) - 510084..510770 (-) 687 WP_011272045.1 ComF family protein -
  BV187_RS02490 (BV187_0508) comE 510783..512120 (-) 1338 WP_011272046.1 type IV pilus secretin PilQ Machinery gene
  BV187_RS02495 (BV187_0509) comD 512130..512543 (-) 414 WP_011272047.1 pilus assembly protein PilP Machinery gene
  BV187_RS02500 (BV187_0510) comC 512540..513061 (-) 522 WP_105893548.1 competence protein ComC Machinery gene
  BV187_RS02505 (BV187_0511) comB 513058..513564 (-) 507 WP_105893549.1 competence protein B Machinery gene
  BV187_RS02510 (BV187_0512) comA 513565..514362 (-) 798 WP_105893550.1 competence protein ComA Machinery gene
  BV187_RS02515 (BV187_0513) - 514461..517061 (+) 2601 WP_105893551.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 137 a.a.        Molecular weight: 15695.85 Da        Isoelectric Point: 4.5625

>NTDB_id=777573 BV187_RS02495 WP_011272047.1 512130..512543(-) (comD) [Haemophilus influenzae strain 93P10H1]
MKHWFFLIILFFMNCSWGQDPFDKTQRNRSQFDNAQTVMEQTEIISSDVPNNLCGADENRQAAEIPLNALKLVGVVISKD
KAFALLQDQGLQIYSVLEGVDVAQEGYIVEKINQNNVQFMRKLGEQCDSSEWKKLSF

Nucleotide


Download         Length: 414 bp        

>NTDB_id=777573 BV187_RS02495 WP_011272047.1 512130..512543(-) (comD) [Haemophilus influenzae strain 93P10H1]
ATGAAACATTGGTTTTTCCTGATTATATTATTTTTTATGAATTGCAGTTGGGGACAAGATCCTTTCGATAAAACACAGCG
TAACCGTTCTCAGTTTGATAACGCACAAACAGTAATGGAGCAGACAGAAATAATTTCCTCAGATGTACCTAATAATCTAT
GCGGAGCGGATGAAAATCGCCAAGCGGCTGAAATTCCTTTGAACGCTTTAAAATTGGTGGGCGTAGTGATTTCTAAAGAT
AAAGCCTTTGCCTTGTTGCAAGATCAAGGTTTGCAAATTTACAGCGTTTTAGAGGGCGTTGATGTGGCTCAAGAGGGCTA
TATTGTAGAAAAAATCAACCAAAACAATGTTCAATTTATGCGTAAGCTCGGAGAGCAATGTGATAGTAGTGAATGGAAAA
AATTAAGTTTTTAA

Domains

Predicted by InterproScan.

Pilus assembly protein, PilP (PilP)

(26-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNA9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Haemophilus influenzae 86-028NP

100

100

1
  comD Haemophilus influenzae Rd KW20

99.27

100

0.993