Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BV189_RS05245 Genome accession   NZ_CP116489
Coordinates   1049978..1050652 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain 93P28H1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1044978..1055652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV189_RS05210 (BV189_1059) rpmG 1045895..1046065 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  BV189_RS05215 (BV189_1060) rpmB 1046077..1046313 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  BV189_RS05220 (BV189_1061) radC 1046526..1047191 (-) 666 WP_041174703.1 RadC family protein -
  BV189_RS05225 (BV189_1062) coaBC 1047355..1048557 (+) 1203 WP_012054541.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  BV189_RS05230 (BV189_1063) dut 1048605..1049060 (+) 456 WP_005631431.1 dUTP diphosphatase -
  BV189_RS05235 (BV189_1064) slmA 1049064..1049720 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  BV189_RS05240 (BV189_1065) - 1049742..1049993 (+) 252 WP_005647999.1 YheU family protein -
  BV189_RS05245 (BV189_1066) crp 1049978..1050652 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  BV189_RS05250 (BV189_1067) rlmC 1051017..1052195 (-) 1179 WP_005686221.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  BV189_RS05255 (BV189_1068) nagZ 1052192..1053244 (-) 1053 WP_005686223.1 beta-N-acetylhexosaminidase -
  BV189_RS05260 (BV189_1069) - 1053248..1053598 (-) 351 WP_005686225.1 YcfL family protein -
  BV189_RS05265 (BV189_1070) - 1053598..1053948 (-) 351 WP_005686227.1 HIT domain-containing protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=777555 BV189_RS05245 WP_005647998.1 1049978..1050652(+) (crp) [Haemophilus influenzae strain 93P28H1]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=777555 BV189_RS05245 WP_005647998.1 1049978..1050652(+) (crp) [Haemophilus influenzae strain 93P28H1]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTACGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42