Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   PFZ59_RS00085 Genome accession   NZ_CP116393
Coordinates   8926..10218 (-) Length   430 a.a.
NCBI ID   WP_208582436.1    Uniprot ID   -
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3926..15218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS00070 (PFZ59_00070) - 6344..7600 (+) 1257 WP_277697753.1 ISL3 family transposase -
  PFZ59_RS00075 (PFZ59_00075) raiA 7649..8191 (-) 543 WP_208582440.1 ribosome-associated translation inhibitor RaiA -
  PFZ59_RS00080 (PFZ59_00080) - 8268..8933 (-) 666 WP_208582438.1 ComF family protein -
  PFZ59_RS00085 (PFZ59_00085) comFA/cflA 8926..10218 (-) 1293 WP_208582436.1 DEAD/DEAH box helicase Machinery gene
  PFZ59_RS00090 (PFZ59_00090) - 10275..10907 (+) 633 WP_277697217.1 YigZ family protein -
  PFZ59_RS00095 (PFZ59_00095) cysK 10997..11923 (+) 927 WP_002937015.1 cysteine synthase A -
  PFZ59_RS00100 (PFZ59_00100) - 11950..12321 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  PFZ59_RS00105 (PFZ59_00105) - 12323..13723 (-) 1401 WP_208582434.1 Cof-type HAD-IIB family hydrolase -
  PFZ59_RS00110 (PFZ59_00110) - 13773..14414 (-) 642 WP_015646507.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48984.50 Da        Isoelectric Point: 9.1510

>NTDB_id=777066 PFZ59_RS00085 WP_208582436.1 8926..10218(-) (comFA/cflA) [Streptococcus suis strain SS/UPM/MY/F001]
MKELENYYGRLFTKYQLTAKEREKAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITRCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYYTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYQAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSRFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=777066 PFZ59_RS00085 WP_208582436.1 8926..10218(-) (comFA/cflA) [Streptococcus suis strain SS/UPM/MY/F001]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAAAAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGATCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAGGTGTTTAAAATGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACCTTAGTTCATGCCGTAACGGGTGCTGGCAAGACAGAAATGATTTACTACACGGTTGCCTCAG
TGATTGATAAAGGTGGGGCAGTCTGTCTGGCCAGTCCACGAATCGATGTTTGTATTGAACTTTATAAGCGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACTCCGTTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCTA
TGCTCTATCAAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGCAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAATCCGCTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAGATTTGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTTCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAGGGTTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACGACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCAGGGTCGGCAGGAGTATGGAACGTCCGACTGGG
TTACTCCAGTTTTATCATGAAGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.285

100

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae D39

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae R6

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae TIGR4

66.589

100

0.667
  comFA/cflA Streptococcus mitis SK321

66.125

100

0.663
  comFA Lactococcus lactis subsp. cremoris KW2

51.773

98.372

0.509
  comFA Latilactobacillus sakei subsp. sakei 23K

37.644

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.349

96.512

0.36