Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QWH96_RS08590 Genome accession   NZ_CP128987
Coordinates   1692258..1692899 (-) Length   213 a.a.
NCBI ID   WP_014612503.1    Uniprot ID   A0A9X9QU89
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NS3396     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1687258..1697899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QWH96_RS08570 (QWH96_08570) - 1688633..1689271 (+) 639 WP_003062333.1 YigZ family protein -
  QWH96_RS08575 (QWH96_08575) cysK 1689375..1690310 (+) 936 WP_003062335.1 cysteine synthase A -
  QWH96_RS08580 (QWH96_08580) - 1690462..1690821 (-) 360 WP_003061410.1 S1 RNA-binding domain-containing protein -
  QWH96_RS08585 (QWH96_08585) - 1690821..1692221 (-) 1401 WP_338433660.1 Cof-type HAD-IIB family hydrolase -
  QWH96_RS08590 (QWH96_08590) vraR 1692258..1692899 (-) 642 WP_014612503.1 response regulator transcription factor Regulator
  QWH96_RS08595 (QWH96_08595) - 1692892..1693896 (-) 1005 WP_003061197.1 sensor histidine kinase -
  QWH96_RS08600 (QWH96_08600) liaF 1693893..1694585 (-) 693 WP_165737340.1 cell wall-active antibiotics response protein LiaF -
  QWH96_RS08605 (QWH96_08605) pknB 1694712..1696607 (-) 1896 WP_003062653.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QWH96_RS08610 (QWH96_08610) - 1696604..1697344 (-) 741 WP_003061786.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23806.38 Da        Isoelectric Point: 4.7966

>NTDB_id=776868 QWH96_RS08590 WP_014612503.1 1692258..1692899(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
MSNIRVILVDDHEMVRMGLKSFLNLQPDIDVIGEASNGREGVELALALKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=776868 QWH96_RS08590 WP_014612503.1 1692258..1692899(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
ATGAGTAACATAAGAGTGATACTAGTGGATGATCATGAAATGGTCCGTATGGGACTTAAAAGTTTTTTGAATTTACAACC
AGATATCGACGTTATTGGCGAAGCTTCTAATGGACGTGAGGGAGTTGAGTTGGCCTTAGCCTTAAAACCAGATGTGCTGG
TTATGGATTTGGTGATGCCAGAATTAGGTGGGGTTGAGGCGACTTTGGAAATCCTCGATAAGTGGAAAGATGCCAAAGTA
TTGGTCTTGACTTCTTATTTGGACAATGAGAAAATTTATCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTCTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAGGTAGACAAAA
AAATTAAAGCGCATGATCAACACCCTGATTTGCATGAAGAGCTAACCGCGCGTGAGTATGATATTTTACATCTTTTAGCT
AAAGGGTATGATAATCAAACTATAGCGGATGAACTTTTCATCTCCTTGAAAACCGTTAAAACGCATGTGTCTAATATTCT
TGCTAAGCTAGAAGTTGATGACCGAACTCAAGCTGTTGTATACGCTTTCCGACACCATTTAGTCCCCCAAGATGATAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9QU89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

97.183

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376