Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   QWH96_RS02885 Genome accession   NZ_CP128987
Coordinates   544133..545485 (+) Length   450 a.a.
NCBI ID   WP_014612101.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NS3396     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 539133..550485
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QWH96_RS02860 (QWH96_02865) - 540200..540847 (-) 648 WP_003057245.1 amino acid ABC transporter permease -
  QWH96_RS02865 (QWH96_02870) - 540862..541563 (-) 702 WP_003057191.1 amino acid ABC transporter permease -
  QWH96_RS02870 (QWH96_02875) - 541577..542377 (-) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  QWH96_RS02875 (QWH96_02880) - 542377..543171 (-) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  QWH96_RS02880 (QWH96_02885) yycF 543430..544140 (+) 711 WP_003057225.1 response regulator YycF -
  QWH96_RS02885 (QWH96_02890) vicK 544133..545485 (+) 1353 WP_014612101.1 cell wall metabolism sensor histidine kinase VicK Regulator
  QWH96_RS02890 (QWH96_02895) vicX 545489..546298 (+) 810 WP_003057211.1 MBL fold metallo-hydrolase Regulator
  QWH96_RS02895 (QWH96_02900) - 546379..547254 (-) 876 WP_046177434.1 helix-turn-helix transcriptional regulator -
  QWH96_RS02900 (QWH96_02905) - 547784..548563 (+) 780 WP_049520212.1 hypothetical protein -
  QWH96_RS02905 (QWH96_02910) - 549007..549750 (+) 744 WP_141668973.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51476.06 Da        Isoelectric Point: 5.7411

>NTDB_id=776829 QWH96_RS02885 WP_014612101.1 544133..545485(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=776829 QWH96_RS02885 WP_014612101.1 544133..545485(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGGTCTGGTAAAATCATCATGATTAACGAGACAGCTCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTTACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterProScan.

PAS fold (PAS)

(95-165)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.188

92

0.673
  micB Streptococcus pneumoniae Cp1015

66.588

94.444

0.629