Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QVM90_RS10730 Genome accession   NZ_CP128979
Coordinates   2096946..2097602 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain TUM1881     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2091946..2102602
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QVM90_RS10700 (QVM90_10700) dcyD 2092825..2093811 (+) 987 WP_264825526.1 D-cysteine desulfhydrase -
  QVM90_RS10705 (QVM90_10705) tcyL 2093826..2094494 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QVM90_RS10710 (QVM90_10710) tcyN 2094491..2095243 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QVM90_RS10715 (QVM90_10715) sdiA 2095473..2096195 (+) 723 WP_097177927.1 transcriptional regulator SdiA -
  QVM90_RS10720 (QVM90_10720) yecF 2096263..2096487 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QVM90_RS10725 (QVM90_10725) yecU 2096474..2096650 (-) 177 WP_000590344.1 protein YecU -
  QVM90_RS28425 - 2096688..2096804 (-) 117 WP_001302039.1 hypothetical protein -
  QVM90_RS10730 (QVM90_10730) letA 2096946..2097602 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QVM90_RS10735 (QVM90_10735) uvrC 2097599..2099431 (+) 1833 WP_001283412.1 excinuclease ABC subunit UvrC Machinery gene
  QVM90_RS10740 (QVM90_10740) pgsA 2099488..2100036 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QVM90_RS10760 (QVM90_10760) - 2100733..2101473 (-) 741 WP_047601063.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=776751 QVM90_RS10730 WP_000611328.1 2096946..2097602(+) (letA) [Escherichia coli strain TUM1881]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=776751 QVM90_RS10730 WP_000611328.1 2096946..2097602(+) (letA) [Escherichia coli strain TUM1881]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482