Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   PF986_RS10435 Genome accession   NZ_CP116013
Coordinates   2163613..2164257 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain SRCM124349     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2158613..2169257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PF986_RS10400 (PF986_10400) - 2159798..2160229 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  PF986_RS10405 (PF986_10405) - 2160229..2160570 (+) 342 WP_022553706.1 Na(+)/H(+) antiporter subunit C -
  PF986_RS10410 (PF986_10410) - 2160563..2162044 (+) 1482 WP_128974217.1 Na+/H+ antiporter subunit D -
  PF986_RS10415 (PF986_10415) - 2162050..2162526 (+) 477 WP_017419419.1 Na+/H+ antiporter subunit E -
  PF986_RS10420 (PF986_10420) - 2162526..2162810 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  PF986_RS10425 (PF986_10425) mnhG 2162794..2163168 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  PF986_RS10430 (PF986_10430) - 2163208..2163591 (-) 384 WP_003152054.1 hotdog fold thioesterase -
  PF986_RS10435 (PF986_10435) comA 2163613..2164257 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  PF986_RS10440 (PF986_10440) comP 2164338..2166647 (-) 2310 WP_260654593.1 histidine kinase Regulator
  PF986_RS10445 (PF986_10445) - 2166667..2166843 (-) 177 WP_087634937.1 competence pheromone ComX -
  PF986_RS10450 (PF986_10450) comQ 2166843..2167781 (-) 939 WP_271243340.1 polyprenyl synthetase family protein Regulator
  PF986_RS10455 (PF986_10455) degQ 2167912..2168052 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  PF986_RS10460 (PF986_10460) - 2168517..2168858 (+) 342 WP_014418765.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=775197 PF986_RS10435 WP_003152052.1 2163613..2164257(-) (comA) [Bacillus velezensis strain SRCM124349]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=775197 PF986_RS10435 WP_003152052.1 2163613..2164257(-) (comA) [Bacillus velezensis strain SRCM124349]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGCAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCAGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCATGTGCTGAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGCTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCTGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGTACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864