Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QUS01_RS11005 Genome accession   NZ_CP128590
Coordinates   2054439..2055095 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain VG35A2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2049439..2060095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUS01_RS10975 (QUS01_10975) dcyD 2050319..2051305 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QUS01_RS10980 (QUS01_10980) tcyL 2051320..2051988 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QUS01_RS10985 (QUS01_10985) tcyN 2051985..2052737 (+) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QUS01_RS10990 (QUS01_10990) sdiA 2052967..2053689 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  QUS01_RS10995 (QUS01_10995) yecF 2053756..2053980 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QUS01_RS11000 (QUS01_11000) yecU 2053967..2054143 (-) 177 WP_000590347.1 protein YecU -
  QUS01_RS25520 - 2054226..2054297 (-) 72 Protein_1984 transcriptional regulator -
  QUS01_RS11005 (QUS01_11005) letA 2054439..2055095 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QUS01_RS11010 (QUS01_11010) uvrC 2055092..2056924 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QUS01_RS11015 (QUS01_11015) pgsA 2056981..2057529 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QUS01_RS11035 (QUS01_11035) yecA 2058178..2058843 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=774696 QUS01_RS11005 WP_000611335.1 2054439..2055095(+) (letA) [Escherichia coli strain VG35A2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=774696 QUS01_RS11005 WP_000611335.1 2054439..2055095(+) (letA) [Escherichia coli strain VG35A2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486