Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QRX22_RS00155 Genome accession   NZ_CP128255
Coordinates   28557..29147 (+) Length   196 a.a.
NCBI ID   WP_001332271.1    Uniprot ID   A0A0H2Z4C4
Organism   Escherichia coli strain T309.Ta3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23557..34147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QRX22_RS00120 (QRX22_00120) yidG 23845..24207 (+) 363 WP_001113432.1 DUF202 domain-containing protein -
  QRX22_RS00125 (QRX22_00125) yidF 24204..24705 (+) 502 Protein_24 radical SAM protein -
  QRX22_RS00130 (QRX22_00130) emrD 24713..25897 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  QRX22_RS00135 (QRX22_00135) ysdE 25979..26053 (+) 75 WP_211180519.1 protein YsdE -
  QRX22_RS00140 (QRX22_00140) ivbL 26298..26396 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  QRX22_RS00145 (QRX22_00145) ilvB 26502..28190 (+) 1689 WP_000168476.1 acetolactate synthase large subunit -
  QRX22_RS00150 (QRX22_00150) ilvN 28194..28484 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QRX22_RS00155 (QRX22_00155) letA 28557..29147 (+) 591 WP_001332271.1 transcriptional regulator UhpA Regulator
  QRX22_RS00160 (QRX22_00160) uhpB 29147..30649 (+) 1503 WP_001445305.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QRX22_RS00165 (QRX22_00165) uhpC 30659..31978 (+) 1320 WP_001350834.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QRX22_RS00170 (QRX22_00170) uhpT 32116..33507 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20836.26 Da        Isoelectric Point: 5.6059

>NTDB_id=773304 QRX22_RS00155 WP_001332271.1 28557..29147(+) (letA) [Escherichia coli strain T309.Ta3]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=773304 QRX22_RS00155 WP_001332271.1 28557..29147(+) (letA) [Escherichia coli strain T309.Ta3]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGTGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTTCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z4C4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378