Detailed information NTG0772368

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PDI57_RS10185
• Genome accession: NZ_CP115476
• Coordinates: 2052886..2053929 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain HP20814-006
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2047886..2058929

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PDI57_RS10155 (PDI57_10155)	-	2048307..2049563 (-)	1257	WP_001795108.1	aminopeptidase	-
PDI57_RS10160 (PDI57_10160)	-	2049566..2049766 (-)	201	WP_000180460.1	DUF1128 family protein	-
PDI57_RS10165 (PDI57_10165)	-	2049913..2050377 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
PDI57_RS10170 (PDI57_10170)	-	2050384..2050659 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PDI57_RS10175 (PDI57_10175)	-	2050937..2052154 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
PDI57_RS10180 (PDI57_10180)	vraR	2052267..2052896 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
PDI57_RS10185 (PDI57_10185)	vraS	2052886..2053929 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PDI57_RS10190 (PDI57_10190)	liaF	2053926..2054627 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
PDI57_RS10195 (PDI57_10195)	-	2054642..2055028 (-)	387	WP_001110179.1	hypothetical protein	-
PDI57_RS10200 (PDI57_10200)	map	2055245..2056003 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PDI57_RS10205 (PDI57_10205)	-	2056475..2057461 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
PDI57_RS10210 (PDI57_10210)	-	2057892..2058305 (-)	414	WP_001557448.1	hypothetical protein	-
PDI57_RS10215 (PDI57_10215)	-	2058334..2058444 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=772368 PDI57_RS10185 WP_001017131.1 2052886..2053929(-) (vraS) [Staphylococcus aureus strain HP20814-006]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=772368 PDI57_RS10185 WP_001017131.1 2052886..2053929(-) (vraS) [Staphylococcus aureus strain HP20814-006]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1