Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   PDI57_RS10585 Genome accession   NZ_CP115476
Coordinates   2129975..2130763 (+) Length   262 a.a.
NCBI ID   WP_223808656.1    Uniprot ID   -
Organism   Staphylococcus aureus strain HP20814-006     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2130806..2132125 2129975..2130763 flank 43


Gene organization within MGE regions


Location: 2129975..2132125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PDI57_RS10585 (PDI57_10585) agrA 2129975..2130763 (+) 789 WP_223808656.1 quorum-sensing response regulator AgrA Regulator
  PDI57_RS10590 (PDI57_10590) - 2130806..2132125 (+) 1320 WP_001557163.1 ISL3-like element IS1181 family transposase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 30706.25 Da        Isoelectric Point: 6.8986

>NTDB_id=772369 PDI57_RS10585 WP_223808656.1 2129975..2130763(+) (agrA) [Staphylococcus aureus strain HP20814-006]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKRFF
IFYGGKVKLPAFFNTQKAQLPL

Nucleotide


Download         Length: 789 bp        

>NTDB_id=772369 PDI57_RS10585 WP_223808656.1 2129975..2130763(+) (agrA) [Staphylococcus aureus strain HP20814-006]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAGGTTCTTC
ATCTTTTATGGTGGGAAGGTAAAACTTCCTGCTTTTTTTAATACACAAAAAGCGCAATTGCCTCTATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

90.458

0.905