Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   QRX37_RS18545 Genome accession   NZ_CP127324
Coordinates   3782218..3782850 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 980-2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3777218..3787850
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QRX37_RS18520 (QRX37_18495) yheS 3777387..3779300 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  QRX37_RS18525 (QRX37_18500) yheT 3779300..3780322 (+) 1023 WP_000057370.1 hydrolase -
  QRX37_RS18530 (QRX37_18505) yheU 3780316..3780534 (+) 219 WP_024704858.1 YheU family protein -
  QRX37_RS18535 (QRX37_18510) prkB 3780588..3781457 (+) 870 WP_001274680.1 phosphoribulokinase -
  QRX37_RS18540 (QRX37_18515) yhfA 3781512..3781916 (-) 405 WP_001148908.1 OsmC family protein -
  QRX37_RS18545 (QRX37_18520) crp 3782218..3782850 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  QRX37_RS18550 (QRX37_18525) yhfK 3782901..3784991 (+) 2091 WP_001571992.1 YccS/YhfK family putative transporter -
  QRX37_RS18555 (QRX37_18530) argD 3785054..3786277 (-) 1224 WP_075861582.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  QRX37_RS18560 (QRX37_18535) pabA 3786363..3786926 (-) 564 WP_000601837.1 aminodeoxychorismate synthase component 2 -
  QRX37_RS18565 (QRX37_18540) fic 3786958..3787560 (-) 603 WP_001280629.1 putative adenosine monophosphate-protein transferase Fic -
  QRX37_RS18570 (QRX37_18545) yhfG 3787550..3787717 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=772330 QRX37_RS18545 WP_000242755.1 3782218..3782850(+) (crp) [Escherichia coli strain 980-2]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=772330 QRX37_RS18545 WP_000242755.1 3782218..3782850(+) (crp) [Escherichia coli strain 980-2]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAAGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467