Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QMY53_RS10705 Genome accession   NZ_CP127265
Coordinates   2161780..2162370 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli TW14425     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2156780..2167370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMY53_RS10675 (QMY53_02092) emrD 2157262..2158446 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  QMY53_RS10680 ysdE 2158528..2158602 (+) 75 WP_211180519.1 protein YsdE -
  QMY53_RS10685 (QMY53_02093) tisB 2158865..2158954 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  QMY53_RS10690 (QMY53_02094) ivbL 2159519..2159617 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  QMY53_RS10695 (QMY53_02095) ilvB 2159723..2161411 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  QMY53_RS10700 (QMY53_02096) ilvN 2161415..2161705 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QMY53_RS10705 (QMY53_02097) letA 2161780..2162370 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QMY53_RS10710 (QMY53_02098) uhpB 2162370..2163872 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QMY53_RS10715 (QMY53_02099) uhpC 2163882..2165201 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QMY53_RS10720 (QMY53_02100) uhpT 2165339..2166730 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=771820 QMY53_RS10705 WP_000633668.1 2161780..2162370(+) (letA) [Escherichia coli TW14425]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=771820 QMY53_RS10705 WP_000633668.1 2161780..2162370(+) (letA) [Escherichia coli TW14425]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378