Detailed information NTG0077157

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: H7K70_RS19515
• Genome accession: NZ_AP022213
• Coordinates: 4209863..4212085 (-)
• Length: 740 a.a.
• NCBI ID: WP_182850582.1
• Uniprot ID: A0A6S5RSN3
• Organism: Metapseudomonas otitidis strain WP8-S17-CRE-03
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4204863..4217085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7K70_RS19480 (WP8S17C03_38140)	murB	4205249..4206268 (-)	1020	WP_182850579.1	UDP-N-acetylmuramate dehydrogenase	-
H7K70_RS19485 (WP8S17C03_38150)	-	4206265..4206726 (-)	462	WP_044404933.1	low molecular weight protein-tyrosine-phosphatase	-
H7K70_RS19490 (WP8S17C03_38160)	kdsB	4206726..4207490 (-)	765	WP_044404936.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
H7K70_RS19495 (WP8S17C03_38170)	-	4207490..4207675 (-)	186	WP_069561688.1	Trm112 family protein	-
H7K70_RS19500 (WP8S17C03_38180)	lpxK	4207711..4208715 (-)	1005	WP_182850580.1	tetraacyldisaccharide 4'-kinase	-
H7K70_RS19505 (WP8S17C03_38190)	-	4208715..4209158 (-)	444	WP_044404945.1	biopolymer transporter ExbD	-
H7K70_RS19510 (WP8S17C03_38200)	-	4209155..4209790 (-)	636	WP_182850581.1	MotA/TolQ/ExbB proton channel family protein	-
H7K70_RS19515 (WP8S17C03_38210)	comA	4209863..4212085 (-)	2223	WP_182850582.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H7K70_RS19520 (WP8S17C03_38220)	-	4212233..4212763 (+)	531	WP_044404954.1	DUF2062 domain-containing protein	-
H7K70_RS19525 (WP8S17C03_38230)	-	4212827..4214071 (-)	1245	WP_074968643.1	lipoprotein-releasing ABC transporter permease subunit	-
H7K70_RS19530 (WP8S17C03_38240)	lolD	4214073..4214756 (-)	684	WP_182852958.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
H7K70_RS19535 (WP8S17C03_38250)	-	4214758..4216008 (-)	1251	WP_182850583.1	lipoprotein-releasing ABC transporter permease subunit	-
H7K70_RS19540 (WP8S17C03_38260)	-	4216105..4216686 (+)	582	WP_044404965.1	PilZ domain-containing protein	-
H7K70_RS19545 (WP8S17C03_38270)	-	4216691..4216984 (+)	294	WP_182850584.1	phosphodiesterase	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 79305.75 Da
• Isoelectric Point: 9.1364

>NTDB_id=77157 H7K70_RS19515 WP_182850582.1 4209863..4212085(-) (comA) [Metapseudomonas otitidis strain WP8-S17-CRE-03]
MRGFWLALASGLLVLRFLPALPPGWLLLGLAGIGAVLLPWRARALGVALIGFAWACHCAQVALDDRLDPALDGTTRWLQG
QVVGLPQQDGGVVRFELVPAAIEGLRLPGRMRVSWYGGPEVRSAETWRLAVTLRRPRGLVNPHTFDYEAWLLARHIGATG
TVKAGERINAAEGPGAWRDDLRQAIQQAEARGRNGTIAALVLGDGSGLSSRDWRHLQDTGTVHLMVISGQHISLLALLLY
GVVAALARLGLWPTRLPWLPCACVLALAGALGYGALAGFDVPVQRACLMTALVLLWRLRFRRLGVVTPLLAVLCIVLLVD
PLASLQAGFWLSFAAVALLVLVFAGRLGSPPAWRSAWRAQWALSLALTPALMALALPISLSGPLANLVAVPWVSFVSVPL
SLAGTALHAVPGLGEGLLLLAGLSLEGLFLLLGWIAEAMPAWQAPALAVWSWGLVLLGCLLLILPPALPFRLPGLLLLVL
LVWPPLQRPAPGTADVRVLDVGQGLAVLVLTEHHALLYDAGPRQGGFDLGERVVVPALRGLGVRHLDELLLSHADNDHSG
GAEAVVRALSVARVISGEVERLPPGLNAQPCEARQWEWDGVHLRTWRWPEARDSNDRSCVLALEANGERLHLTGDLGQAA
EAAWVESGEPLAADWLLAPHHGSRSSSSARLLQAVRPRGALISRGARNAFGHPHPQVLARYRALPAALYDTAESGALLIR
LGTHGEVSGLRSQARFWREK

Nucleotide

• Length: 2223 bp

>NTDB_id=77157 H7K70_RS19515 WP_182850582.1 4209863..4212085(-) (comA) [Metapseudomonas otitidis strain WP8-S17-CRE-03]
ATGCGAGGTTTCTGGCTGGCCCTGGCCAGCGGGCTGCTGGTGCTGCGCTTCCTGCCGGCGCTGCCGCCCGGTTGGCTGCT
GCTGGGGCTGGCGGGCATCGGCGCGGTGCTGCTGCCCTGGCGGGCGCGAGCGCTGGGCGTCGCCCTGATTGGCTTCGCCT
GGGCCTGTCACTGCGCCCAGGTCGCCCTCGACGACCGGCTCGACCCGGCGCTGGACGGCACCACCCGCTGGCTGCAGGGG
CAGGTGGTCGGCCTGCCGCAGCAGGACGGCGGCGTGGTGCGCTTCGAACTGGTGCCCGCCGCCATCGAAGGGCTGCGCCT
GCCCGGGCGGATGCGGGTGTCCTGGTACGGCGGTCCGGAGGTGCGCAGCGCCGAGACCTGGCGACTGGCCGTCACCCTTC
GCCGCCCGCGTGGCCTGGTGAACCCCCACACCTTCGACTACGAGGCCTGGCTGCTGGCCCGGCATATCGGCGCCACCGGC
ACGGTGAAGGCGGGCGAACGGATCAACGCGGCCGAAGGGCCCGGCGCCTGGCGTGACGACCTGCGCCAGGCCATCCAGCA
GGCTGAGGCGCGGGGGCGCAACGGCACCATCGCCGCGCTGGTCCTGGGTGATGGCTCCGGTCTCAGCAGCCGCGACTGGC
GGCACCTGCAGGACACCGGCACGGTCCACCTGATGGTCATCTCCGGGCAGCACATCTCCCTGCTGGCACTGCTGCTCTAC
GGTGTCGTGGCCGCCCTGGCCCGGCTCGGGCTCTGGCCAACGCGCCTGCCCTGGCTGCCCTGTGCCTGCGTGCTGGCTCT
GGCCGGCGCCCTCGGCTATGGGGCGCTGGCCGGGTTCGACGTACCGGTGCAGCGCGCCTGCCTGATGACCGCCCTGGTGC
TGCTCTGGCGCCTGCGTTTCCGCCGGCTCGGGGTGGTCACGCCGCTGTTGGCGGTGCTTTGTATCGTGCTGCTGGTGGAT
CCGCTGGCCTCCCTGCAGGCGGGCTTCTGGCTCTCCTTCGCGGCCGTGGCGCTGCTGGTGCTGGTGTTCGCCGGGCGCCT
GGGCAGCCCGCCGGCTTGGCGCAGCGCGTGGCGGGCACAGTGGGCCCTGAGCCTGGCGCTGACCCCGGCGCTGATGGCCC
TCGCCCTGCCCATCAGCCTCAGCGGCCCCCTGGCCAACCTGGTGGCGGTGCCCTGGGTCAGCTTCGTCTCGGTGCCGCTG
TCCCTGGCCGGCACGGCCCTGCACGCCGTGCCCGGCCTGGGTGAGGGCCTGCTGTTGCTGGCGGGGCTTTCCCTGGAGGG
GCTCTTCCTTCTATTGGGCTGGATCGCCGAGGCGATGCCGGCGTGGCAGGCGCCTGCGCTGGCGGTCTGGAGCTGGGGCC
TGGTGCTGCTGGGCTGCCTGCTGCTGATCCTGCCGCCGGCGCTGCCCTTTCGCCTGCCGGGGCTGCTGTTGCTGGTGCTG
CTGGTTTGGCCGCCCCTGCAGCGGCCCGCGCCCGGTACGGCGGATGTCCGCGTGCTGGACGTGGGGCAGGGTCTGGCGGT
GCTGGTGCTCACCGAGCACCACGCCTTGCTGTATGACGCCGGCCCGCGCCAGGGCGGCTTCGACCTGGGCGAGCGGGTGG
TGGTGCCGGCCCTGCGCGGGCTGGGTGTACGGCATCTGGACGAACTGCTGCTGAGCCACGCCGACAACGACCATTCCGGC
GGGGCCGAGGCGGTGGTGCGCGCACTGTCCGTGGCGCGGGTGATCAGCGGCGAGGTGGAGCGCCTGCCGCCCGGCCTCAA
TGCCCAGCCCTGCGAAGCCCGCCAGTGGGAGTGGGATGGCGTGCACCTGCGCACCTGGCGCTGGCCCGAGGCCCGCGACA
GCAATGATCGCTCCTGCGTGCTCGCCCTCGAGGCCAACGGCGAGCGCCTGCACCTGACCGGCGACCTCGGCCAGGCCGCC
GAAGCCGCCTGGGTGGAGAGCGGCGAGCCCCTCGCTGCGGACTGGCTGCTGGCGCCCCACCATGGCAGTCGCAGCTCCTC
CTCGGCGCGCCTGCTGCAGGCGGTGCGGCCGCGCGGGGCACTGATCTCCCGGGGCGCGCGCAACGCCTTCGGTCATCCCC
ATCCCCAGGTGCTGGCGCGTTACCGTGCGCTGCCGGCGGCTCTTTACGACACCGCCGAGTCCGGCGCGCTGCTGATTCGC
CTGGGCACCCACGGCGAGGTGTCGGGACTGCGGAGCCAGGCACGTTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (200-465)

• Domain of unknown function (DUF4131) (DUF4131) (20-167)

• Metallo-beta-lactamase superfamily (Lactamase_B) (500-683)

3D structure

• AlphaFold DB: A0A6S5RSN3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	61.978	97.027	0.601
comA	Ralstonia pseudosolanacearum GMI1000	35.077	100	0.399