Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQC31_RS14945 Genome accession   NZ_CP127004
Coordinates   3002213..3002803 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain YZ3-11     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2997213..3007803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQC31_RS14915 (QQC31_14875) emrD 2997695..2998879 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  QQC31_RS14920 (QQC31_14880) ysdE 2998961..2999035 (+) 75 WP_211180519.1 protein YsdE -
  QQC31_RS14925 (QQC31_14885) tisB 2999298..2999387 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  QQC31_RS14930 (QQC31_14890) ivbL 2999952..3000050 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  QQC31_RS14935 (QQC31_14895) ilvB 3000156..3001844 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  QQC31_RS14940 (QQC31_14900) ilvN 3001848..3002138 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QQC31_RS14945 (QQC31_14905) letA 3002213..3002803 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QQC31_RS14950 (QQC31_14910) uhpB 3002803..3004305 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QQC31_RS14955 (QQC31_14915) uhpC 3004315..3005634 (+) 1320 WP_001402648.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QQC31_RS14960 (QQC31_14920) uhpT 3005890..3007281 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=769840 QQC31_RS14945 WP_000633668.1 3002213..3002803(+) (letA) [Escherichia coli strain YZ3-11]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=769840 QQC31_RS14945 WP_000633668.1 3002213..3002803(+) (letA) [Escherichia coli strain YZ3-11]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378