Detailed information NTG0769628

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: QP018_RS09280
• Genome accession: NZ_CP126975
• Coordinates: 1947290..1948432 (-)
• Length: 380 a.a.
• NCBI ID: WP_285092016.1
• Uniprot ID: A0AAX3XDG8
• Organism: Gallibacterium anatis strain BJF12
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1942290..1953432

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QP018_RS09255 (QP018_09255)	secM	1943787..1944122 (-)	336	WP_285092025.1	secA translation cis-regulator SecM	-
QP018_RS09260 (QP018_09260)	-	1944213..1944554 (+)	342	WP_039091335.1	DciA family protein	-
QP018_RS09265 (QP018_09265)	-	1944514..1945413 (-)	900	WP_285092021.1	Dam family site-specific DNA-(adenine-N6)-methyltransferase	-
QP018_RS09270 (QP018_09270)	aroB	1945417..1946508 (-)	1092	WP_285092019.1	3-dehydroquinate synthase	-
QP018_RS09275 (QP018_09275)	aroK	1946543..1947070 (-)	528	WP_013746277.1	shikimate kinase AroK	-
QP018_RS09280 (QP018_09280)	comE	1947290..1948432 (-)	1143	WP_285092016.1	type IV pilus secretin PilQ	Machinery gene
QP018_RS09285 (QP018_09285)	-	1948432..1948962 (-)	531	WP_039080709.1	hypothetical protein	-
QP018_RS09290 (QP018_09290)	-	1948962..1949516 (-)	555	WP_285092013.1	hypothetical protein	-
QP018_RS09295 (QP018_09295)	-	1949506..1950180 (-)	675	WP_230585712.1	hypothetical protein	-
QP018_RS09300 (QP018_09300)	-	1950381..1952942 (+)	2562	WP_285092007.1	transglycosylase domain-containing protein	-

Sequence

Protein

• Length: 380 a.a.
• Molecular weight: 42164.26 Da
• Isoelectric Point: 5.4736

>NTDB_id=769628 QP018_RS09280 WP_285092016.1 1947290..1948432(-) (comE) [Gallibacterium anatis strain BJF12]
MKKGIILVVCMMMSLSGWSKKVILDPFFAEEANIMPDLIEDKNLIPTDEFEAIAVKYIQVNELYKIFNENGNGLLSGLSG
FSVEPSNNLLLVKGDKQQIQKFKQLISQLDKPGKQIAIEARIVTINNESLNELGVRWGMFSDADNFHKVAAKFDSFGLEN
LSSHLNVNFSTSSEAASIALQVAKIHGRLLDLELKALEQENNVEIIASPHLLTSNQRKASIKQGSEIPYVIEDDTERSSR
THIEFKEAVLGLEVTPQVLYQGVISLDLVVTQNSAGASIPYGAGQVVTIDKQEVQSQVLVRDGETVVLGGIFHDLIGKGE
NKVPLLGDIPGLGKLFSSKSERHQKRELVIFITPRIIHNSQETIENYQKRKQDFIQGNNL

Nucleotide

• Length: 1143 bp

>NTDB_id=769628 QP018_RS09280 WP_285092016.1 1947290..1948432(-) (comE) [Gallibacterium anatis strain BJF12]
ATGAAGAAAGGCATAATACTGGTGGTTTGTATGATGATGTCATTGAGCGGTTGGAGTAAAAAAGTGATATTAGATCCTTT
TTTTGCGGAAGAGGCGAATATAATGCCTGACTTAATAGAGGATAAAAATTTGATTCCGACAGATGAATTTGAAGCAATTG
CTGTGAAATATATACAAGTGAATGAATTGTATAAAATTTTTAATGAAAACGGTAATGGGCTTTTGTCCGGCTTGAGCGGA
TTTAGTGTCGAACCGAGCAACAATTTATTGTTGGTGAAAGGGGATAAGCAACAGATACAAAAATTTAAACAGTTAATTTC
TCAACTGGATAAACCGGGTAAGCAGATTGCCATAGAAGCACGCATAGTGACGATTAATAATGAAAGTTTAAATGAGCTTG
GCGTTCGTTGGGGAATGTTCAGTGATGCGGATAATTTTCACAAAGTGGCAGCTAAATTTGATAGTTTTGGTTTAGAAAAT
TTAAGTTCTCACTTAAATGTTAATTTTTCCACGAGTTCGGAGGCGGCATCTATTGCATTACAGGTGGCAAAAATTCACGG
ACGGTTGCTGGATTTAGAGTTAAAAGCGTTGGAACAGGAAAATAATGTGGAAATTATTGCCAGTCCACATTTATTGACAT
CTAACCAAAGAAAGGCGTCGATTAAGCAAGGTTCTGAAATTCCTTATGTTATCGAAGATGATACAGAACGCAGCAGCCGT
ACTCATATTGAATTTAAAGAGGCAGTATTGGGTTTGGAAGTGACCCCACAAGTGCTGTATCAAGGCGTGATCTCACTGGA
TTTGGTGGTAACACAGAATTCAGCCGGTGCGAGTATTCCTTATGGTGCCGGGCAAGTGGTAACGATTGATAAACAGGAAG
TGCAATCGCAAGTGTTGGTGAGAGATGGAGAAACGGTGGTGTTGGGCGGTATTTTTCACGATCTGATCGGAAAAGGTGAA
AATAAAGTACCGTTGTTGGGGGATATTCCCGGATTAGGTAAGTTATTCAGTAGCAAATCGGAGCGTCATCAGAAGCGTGA
GCTGGTGATTTTTATTACACCAAGAATTATTCATAATTCTCAAGAAACGATAGAAAATTATCAAAAGCGTAAACAGGATT
TTATACAAGGAAACAATCTTTGA

Domains

Predicted by InterProScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (52-115)

• Bacterial type II and III secretion system protein (Secretin) (196-358)

3D structure

• AlphaFold DB: A0AAX3XDG8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae 86-028NP	53.438	84.211	0.45
comE	Haemophilus influenzae Rd KW20	53.106	84.737	0.45
comE	Glaesserella parasuis strain SC1401	49.841	82.895	0.413
pilQ	Vibrio campbellii strain DS40M4	42.508	86.053	0.366