Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   LPH32_RS16485 Genome accession   NZ_AP025214
Coordinates   3392956..3393588 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2017.09.02CC     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3387956..3398588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPH32_RS16460 (VEGS19_A31280) yhfG 3388088..3388255 (+) 168 WP_000736860.1 YhfG family protein -
  LPH32_RS16465 (VEGS19_A31290) fic 3388245..3388847 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  LPH32_RS16470 (VEGS19_A31300) pabA 3388879..3389442 (+) 564 WP_053290844.1 aminodeoxychorismate synthase component 2 -
  LPH32_RS16475 (VEGS19_A31310) argD 3389528..3390748 (+) 1221 WP_000963803.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  LPH32_RS16480 (VEGS19_A31320) yhfK 3390815..3392905 (-) 2091 WP_001571992.1 YccS/YhfK family putative transporter -
  LPH32_RS16485 (VEGS19_A31330) crp 3392956..3393588 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  LPH32_RS16490 (VEGS19_A31340) yhfA 3393890..3394294 (+) 405 WP_001148908.1 OsmC family protein -
  LPH32_RS16495 (VEGS19_A31350) prkB 3394349..3395218 (-) 870 WP_001274680.1 phosphoribulokinase -
  LPH32_RS16500 (VEGS19_A31360) yheU 3395272..3395490 (-) 219 WP_000907085.1 YheU family protein -
  LPH32_RS16505 (VEGS19_A31370) yheT 3395484..3396506 (-) 1023 WP_042103628.1 hydrolase -
  LPH32_RS16510 (VEGS19_A31380) yheS 3396506..3398419 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=76942 LPH32_RS16485 WP_000242755.1 3392956..3393588(-) (crp) [Escherichia coli strain 2017.09.02CC]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=76942 LPH32_RS16485 WP_000242755.1 3392956..3393588(-) (crp) [Escherichia coli strain 2017.09.02CC]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment