Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   O6U12_RS20500 Genome accession   NZ_CP114899
Coordinates   3878225..3879382 (+) Length   385 a.a.
NCBI ID   WP_003227983.1    Uniprot ID   A0A199WDV9
Organism   Bacillus subtilis strain     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3873225..3884382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6U12_RS20480 (O6U12_20480) tuaH 3873693..3874886 (+) 1194 WP_072557276.1 teichuronic acid biosynthesis protein TuaH -
  O6U12_RS20485 (O6U12_20485) tagO 3875031..3876107 (+) 1077 WP_003227975.1 MraY family glycosyltransferase -
  O6U12_RS20490 (O6U12_20490) tagV 3876180..3877355 (-) 1176 WP_017695311.1 polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV -
  O6U12_RS20495 (O6U12_20495) yvyE 3877355..3878008 (-) 654 WP_003227979.1 YigZ family protein -
  O6U12_RS20500 (O6U12_20500) degS 3878225..3879382 (+) 1158 WP_003227983.1 two-component sensor histidine kinase DegS Regulator
  O6U12_RS20505 (O6U12_20505) degU 3879465..3880154 (+) 690 WP_003219701.1 two-component system response regulator DegU Regulator
  O6U12_RS20510 (O6U12_20510) fakBA 3880252..3881097 (+) 846 WP_017695310.1 DegV family protein -
  O6U12_RS20515 (O6U12_20515) comFA 3881203..3882594 (+) 1392 WP_017695309.1 ATP-dependent helicase ComFA Machinery gene
  O6U12_RS20520 (O6U12_20520) comFB 3882646..3882928 (+) 283 Protein_3992 late competence development ComFB family protein -
  O6U12_RS20525 (O6U12_20525) comFC 3882892..3883614 (+) 723 WP_026113628.1 comF operon protein ComFC Machinery gene
  O6U12_RS20530 (O6U12_20530) yvyF 3883688..3884107 (+) 420 WP_017695307.1 TIGR03826 family flagellar region protein -

Sequence

Protein


Download         Length: 385 a.a.        Molecular weight: 44957.76 Da        Isoelectric Point: 6.2957

>NTDB_id=767625 O6U12_RS20500 WP_003227983.1 3878225..3879382(+) (degS) [Bacillus subtilis strain]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide


Download         Length: 1158 bp        

>NTDB_id=767625 O6U12_RS20500 WP_003227983.1 3878225..3879382(+) (degS) [Bacillus subtilis strain]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATCATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(180-248)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)

Sensor protein DegS (DegS)

(12-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WDV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

100

100

1