Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   LPH27_RS01910 Genome accession   NZ_AP025205
Coordinates   425248..425880 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2017.04.03CC     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 420248..430880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPH27_RS01885 (VEGS17_A03770) yhfG 420380..420547 (+) 168 WP_229266231.1 YhfG family protein -
  LPH27_RS01890 (VEGS17_A03780) fic 420537..421139 (+) 603 WP_229266232.1 putative adenosine monophosphate-protein transferase Fic -
  LPH27_RS01895 (VEGS17_A03790) pabA 421171..421734 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  LPH27_RS01900 (VEGS17_A03800) argD 421820..423040 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  LPH27_RS01905 (VEGS17_A03810) yhfK 423107..425197 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  LPH27_RS01910 (VEGS17_A03820) crp 425248..425880 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  LPH27_RS01915 (VEGS17_A03830) yhfA 426182..426586 (+) 405 WP_001148908.1 OsmC family protein -
  LPH27_RS01920 (VEGS17_A03840) prkB 426641..427510 (-) 870 WP_001274680.1 phosphoribulokinase -
  LPH27_RS01925 (VEGS17_A03850) yheU 427564..427782 (-) 219 WP_000907085.1 YheU family protein -
  LPH27_RS01930 (VEGS17_A03860) yheT 427776..428798 (-) 1023 WP_000057356.1 hydrolase -
  LPH27_RS01935 (VEGS17_A03870) yheS 428798..430711 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=76735 LPH27_RS01910 WP_000242755.1 425248..425880(-) (crp) [Escherichia coli strain 2017.04.03CC]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=76735 LPH27_RS01910 WP_000242755.1 425248..425880(-) (crp) [Escherichia coli strain 2017.04.03CC]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment