Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   O3S97_RS04260 Genome accession   NZ_CP114450
Coordinates   897324..898040 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain SE 4.8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 892324..903040
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O3S97_RS04245 (O3S97_04250) - 893605..894558 (+) 954 WP_002497209.1 LacI family DNA-binding transcriptional regulator -
  O3S97_RS04250 (O3S97_04255) - 894818..896290 (+) 1473 WP_002501553.1 sucrose-6-phosphate hydrolase -
  O3S97_RS04255 (O3S97_04260) - 896297..897256 (+) 960 WP_060546487.1 carbohydrate kinase -
  O3S97_RS04260 (O3S97_04265) agrA 897324..898040 (-) 717 WP_002447515.1 LytTR family DNA-binding domain-containing protein Regulator
  O3S97_RS04265 (O3S97_04270) - 898057..899346 (-) 1290 WP_060546485.1 GHKL domain-containing protein -
  O3S97_RS04270 (O3S97_04275) - 899372..899512 (-) 141 WP_002490348.1 cyclic lactone autoinducer peptide -
  O3S97_RS04275 (O3S97_04280) - 899518..900081 (-) 564 WP_060546483.1 accessory gene regulator AgrB -
  O3S97_RS04280 (O3S97_04285) hld 900398..900475 (+) 78 WP_002494082.1 delta-hemolysin -
  O3S97_RS04285 (O3S97_04290) - 900855..901640 (-) 786 WP_060546481.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=765981 O3S97_RS04260 WP_002447515.1 897324..898040(-) (agrA) [Staphylococcus epidermidis strain SE 4.8]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=765981 O3S97_RS04260 WP_002447515.1 897324..898040(-) (agrA) [Staphylococcus epidermidis strain SE 4.8]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTTTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374