Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QNK08_RS07285 Genome accession   NZ_CP125983
Coordinates   1378295..1379644 (-) Length   449 a.a.
NCBI ID   WP_033881739.1    Uniprot ID   -
Organism   Bacillus subtilis strain ZKY04     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1373295..1384644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QNK08_RS07265 (QNK08_07280) mhqA 1373495..1374445 (+) 951 WP_014479571.1 ring-cleaving dioxygenase -
  QNK08_RS07270 (QNK08_07285) - 1374554..1374649 (+) 96 Protein_1369 hypothetical protein -
  QNK08_RS07275 (QNK08_07290) ykcB 1374662..1376812 (+) 2151 WP_259607668.1 glycosyltransferase family 39 protein -
  QNK08_RS07280 (QNK08_07295) gtcC 1376824..1377795 (+) 972 WP_014479573.1 glycosyltransferase family 2 protein -
  QNK08_RS07285 (QNK08_07300) htrA 1378295..1379644 (-) 1350 WP_033881739.1 serine protease HtrA Regulator
  QNK08_RS07290 (QNK08_07305) proG 1379813..1380631 (+) 819 WP_014479575.1 pyrroline-5-carboxylate reductase ProG -
  QNK08_RS07295 (QNK08_07310) dppA 1380761..1381585 (+) 825 WP_014479576.1 D-aminopeptidase DppA -
  QNK08_RS07300 (QNK08_07315) dppB 1381602..1382528 (+) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  QNK08_RS07305 (QNK08_07320) dppC 1382534..1383496 (+) 963 WP_069964127.1 dipeptide ABC transporter permease DppC -
  QNK08_RS07310 (QNK08_07325) dppD 1383501..1384508 (+) 1008 WP_014479578.1 dipeptide ABC transporter ATP-binding subunit DppD -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 47728.87 Da        Isoelectric Point: 4.6021

>NTDB_id=765970 QNK08_RS07285 WP_033881739.1 1378295..1379644(-) (htrA) [Bacillus subtilis strain ZKY04]
MDNYRDENRTKGNENEVFLTKENDQSASYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAK
QSSSQQQTQSVTATSTSSESKKSSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG
SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGETVIA
IGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFA
IPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIIIGLK
GKEIDTGSELRNILYKDAKIGETVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=765970 QNK08_RS07285 WP_033881739.1 1378295..1379644(-) (htrA) [Bacillus subtilis strain ZKY04]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTAATGAGAATGAGGTCTTTTTAACGAAAGAGAACGATCAGAGCGC
CTCCTACTCGGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGATTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTCGCCCTTGGCATTTACACGTTTACACCGCTTGGCGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCTCTGAATCTAAAAAAAGCTCAAGCAGCTC
ATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCGGTATTACAA
ATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGCGGTTCAGGG
TCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGCATCATCACT
GAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAGCCGTCCTCC
AAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTTAGAACAGGCGAGACCGTTATTGCG
ATTGGGGATCCGCTTGGAAAAGACCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAACGGTTTCAAT
GTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACAGACGCAGCAATTAATCCAGGTAACAGCGGCGGTCCTT
TGTTAAATACAGACGGCAAAATTGTCGGCATTAACAGTATGAAAATCAGTGAGGATGATGTTGAGGGCATCGGATTTGCC
ATTCCAAGCAATGACGTAAAACCGATTGCTGAAGAACTGCTGTCTAAAGGCCAAATTGAACGTCCATATATCGGTGTCAG
CATGCTTGATCTGGAACAAGTGCCGCAAAATTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGAATAAAGGTG
TTTACATCCGTGAGGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCGGAGGATATTATCATCGGCCTAAAA
GGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGAAACCGTTGAAGTGAA
AATTCTCCGAAACGGCAAAGAAATGACGAAAAAAATTAAACTTGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(160-304)

PDZ domain (PDZ_2)

(342-441)

Peptidase family M50 (Peptidase_M50)

(366-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

40.796

89.532

0.365
  htrA Streptococcus pneumoniae D39

40.796

89.532

0.365
  htrA Streptococcus pneumoniae R6

40.796

89.532

0.365
  htrA Streptococcus pneumoniae TIGR4

40.796

89.532

0.365
  htrA Streptococcus mitis NCTC 12261

39.32

91.759

0.361