Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QMY08_RS04595 Genome accession   NZ_CP125889
Coordinates   866088..866744 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EPSSH018     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 861088..871744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMY08_RS04565 (QMY08_04545) yecA 862339..863004 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  QMY08_RS04585 (QMY08_04565) pgsA 863654..864202 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QMY08_RS04590 (QMY08_04570) uvrC 864259..866091 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  QMY08_RS04595 (QMY08_04575) letA 866088..866744 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QMY08_RS04600 - 866886..867002 (+) 117 WP_001302039.1 hypothetical protein -
  QMY08_RS04605 (QMY08_04580) yecU 867040..867216 (+) 177 WP_123004597.1 protein YecU -
  QMY08_RS04610 (QMY08_04585) yecF 867203..867427 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QMY08_RS04615 (QMY08_04590) sdiA 867495..868217 (-) 723 WP_001461118.1 transcriptional regulator SdiA -
  QMY08_RS04620 (QMY08_04595) tcyN 868447..869199 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QMY08_RS04625 (QMY08_04600) tcyL 869196..869864 (-) 669 WP_309598089.1 cystine ABC transporter permease -
  QMY08_RS04630 (QMY08_04605) dcyD 869879..870865 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=764912 QMY08_RS04595 WP_000611328.1 866088..866744(-) (letA) [Escherichia coli strain EPSSH018]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=764912 QMY08_RS04595 WP_000611328.1 866088..866744(-) (letA) [Escherichia coli strain EPSSH018]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482