Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QMY17_RS14930 Genome accession   NZ_CP125812
Coordinates   2782046..2783395 (+) Length   449 a.a.
NCBI ID   WP_033881739.1    Uniprot ID   -
Organism   Bacillus subtilis strain N3378-3At     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2777046..2788395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMY17_RS14905 dppD 2777182..2778189 (-) 1008 WP_014479578.1 dipeptide ABC transporter ATP-binding subunit DppD -
  QMY17_RS14910 dppC 2778194..2779156 (-) 963 WP_014479577.1 dipeptide ABC transporter permease DppC -
  QMY17_RS14915 dppB 2779162..2780088 (-) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  QMY17_RS14920 dppA 2780105..2780929 (-) 825 WP_014479576.1 D-aminopeptidase DppA -
  QMY17_RS14925 proG 2781059..2781877 (-) 819 WP_014479575.1 pyrroline-5-carboxylate reductase ProG -
  QMY17_RS14930 htrA 2782046..2783395 (+) 1350 WP_033881739.1 serine protease HtrA Regulator
  QMY17_RS14935 gtcC 2783895..2784866 (-) 972 WP_014479573.1 glycosyltransferase family 2 protein -
  QMY17_RS14940 ykcB 2784878..2787028 (-) 2151 WP_014479572.1 glycosyltransferase family 39 protein -
  QMY17_RS14945 - 2787041..2787136 (-) 96 Protein_2942 hypothetical protein -
  QMY17_RS14950 mhqA 2787245..2788195 (-) 951 WP_014479571.1 ring-cleaving dioxygenase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 47728.87 Da        Isoelectric Point: 4.6021

>NTDB_id=764174 QMY17_RS14930 WP_033881739.1 2782046..2783395(+) (htrA) [Bacillus subtilis strain N3378-3At]
MDNYRDENRTKGNENEVFLTKENDQSASYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAK
QSSSQQQTQSVTATSTSSESKKSSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG
SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGETVIA
IGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFA
IPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIIIGLK
GKEIDTGSELRNILYKDAKIGETVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=764174 QMY17_RS14930 WP_033881739.1 2782046..2783395(+) (htrA) [Bacillus subtilis strain N3378-3At]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTAATGAGAATGAGGTCTTTTTAACGAAAGAGAACGATCAGAGCGC
CTCCTACTCGGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGATTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTCGCCCTTGGCATTTACACGTTTACACCGCTTGGCGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCTCTGAATCTAAAAAAAGCTCAAGCAGCTC
ATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCGGTATTACAA
ATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGCGGTTCAGGG
TCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGCATCATCACT
GAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAGCCGTCCTCC
AAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTTAGAACAGGCGAGACCGTTATTGCG
ATTGGGGATCCGCTTGGAAAAGACCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAACGGTTTCAAT
GTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACAGACGCAGCAATTAATCCAGGTAACAGCGGCGGTCCTT
TGTTAAATACAGACGGCAAAATTGTCGGCATTAACAGTATGAAAATCAGTGAGGATGATGTTGAGGGCATCGGATTTGCC
ATTCCAAGCAATGACGTAAAACCGATTGCTGAAGAACTGCTGTCTAAAGGCCAAATTGAACGTCCATATATCGGTGTCAG
CATGCTTGATCTGGAACAAGTGCCGCAAAATTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGAATAAAGGTG
TTTACATCCGTGAGGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCGGAGGATATTATCATCGGCCTAAAA
GGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGAAACCGTTGAAGTGAA
AATTCTCCGAAACGGCAAAGAAATGACGAAAAAAATTAAACTTGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(160-304)

PDZ domain (PDZ_2)

(342-441)

Peptidase family M50 (Peptidase_M50)

(366-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

40.796

89.532

0.365
  htrA Streptococcus pneumoniae D39

40.796

89.532

0.365
  htrA Streptococcus pneumoniae R6

40.796

89.532

0.365
  htrA Streptococcus pneumoniae TIGR4

40.796

89.532

0.365
  htrA Streptococcus mitis NCTC 12261

39.32

91.759

0.361