Detailed information NTG0764162

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: OZA25_RS05110
• Genome accession: NZ_CP114038
• Coordinates: 998422..999585 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain B8
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 993422..1004585

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OZA25_RS05090 (OZA25_05090)	tuaH	993862..995058 (+)	1197	WP_032876154.1	teichuronic acid biosynthesis protein TuaH	-
OZA25_RS05095 (OZA25_05095)	-	995191..996267 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
OZA25_RS05100 (OZA25_05100)	-	996366..997547 (-)	1182	WP_032876157.1	LCP family protein	-
OZA25_RS05105 (OZA25_05105)	-	997552..998199 (-)	648	WP_007614107.1	YigZ family protein	-
OZA25_RS05110 (OZA25_05110)	degS	998422..999585 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
OZA25_RS05115 (OZA25_05115)	degU	999662..1000351 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
OZA25_RS05120 (OZA25_05120)	-	1000449..1001297 (+)	849	WP_032876160.1	DegV family protein	-
OZA25_RS05125 (OZA25_05125)	comFA	1001406..1002791 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
OZA25_RS05130 (OZA25_05130)	-	1002849..1003133 (+)	285	WP_003151389.1	late competence development ComFB family protein	-
OZA25_RS05135 (OZA25_05135)	comFC	1003139..1003828 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
OZA25_RS05140 (OZA25_05140)	-	1003902..1004321 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=764162 OZA25_RS05110 WP_007407484.1 998422..999585(+) (degS) [Bacillus velezensis strain B8]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=764162 OZA25_RS05110 WP_007407484.1 998422..999585(+) (degS) [Bacillus velezensis strain B8]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951