Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QL281_RS19585 Genome accession   NZ_CP125292
Coordinates   3662715..3664064 (-) Length   449 a.a.
NCBI ID   WP_041333853.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM117797     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 3657715..3669064
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QL281_RS19560 (QL281_19560) mhqA 3657878..3658828 (+) 951 WP_014476561.1 ring-cleaving dioxygenase -
  QL281_RS19565 (QL281_19565) - 3658937..3659038 (+) 102 Protein_3795 hypothetical protein -
  QL281_RS19570 (QL281_19570) ykcB 3659046..3661214 (+) 2169 WP_041333859.1 glycosyltransferase family 39 protein -
  QL281_RS19575 (QL281_19575) ykcC 3661226..3662197 (+) 972 WP_041333856.1 glycosyltransferase family 2 protein -
  QL281_RS19580 (QL281_19580) - 3662381..3662557 (-) 177 WP_003245413.1 hypothetical protein -
  QL281_RS19585 (QL281_19585) htrA 3662715..3664064 (-) 1350 WP_041333853.1 serine protease HtrA Regulator
  QL281_RS19590 (QL281_19590) proG 3664233..3665051 (+) 819 WP_041333850.1 pyrroline-5-carboxylate reductase ProG -
  QL281_RS19595 (QL281_19595) dppA 3665180..3666004 (+) 825 WP_014479576.1 D-aminopeptidase DppA -
  QL281_RS19600 (QL281_19600) dppB 3666021..3666947 (+) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  QL281_RS19605 (QL281_19605) dppC 3666953..3667915 (+) 963 WP_014476568.1 dipeptide ABC transporter permease DppC -
  QL281_RS19610 (QL281_19610) dppD 3667920..3668927 (+) 1008 WP_041333846.1 dipeptide ABC transporter ATP-binding subunit DppD -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 47744.87 Da        Isoelectric Point: 4.5990

>NTDB_id=762322 QL281_RS19585 WP_041333853.1 3662715..3664064(-) (htrA) [Bacillus subtilis strain SRCM117797]
MDNYRDENRTKGNENEVFLTKENDQSTSYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAK
QSSSQQQTQSVTATSTSSESKKSSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG
SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGETVIA
IGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFA
IPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIIIGLK
GKEIDTGSELRNILYKDAKIGDTVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=762322 QL281_RS19585 WP_041333853.1 3662715..3664064(-) (htrA) [Bacillus subtilis strain SRCM117797]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTAATGAGAATGAGGTCTTTTTAACGAAAGAGAACGATCAGAGCAC
CTCCTACTCGGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGATTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTTGCCCTTGGCATTTACACGTTTACACCGCTTGGTGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCTCTGAATCTAAAAAAAGCTCAAGCAGCTC
ATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCGGTATTACAA
ATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGCGGTTCAGGG
TCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGCATCATCACT
GAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAGCCGTCCTCC
AAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTTAGAACAGGCGAGACCGTTATTGCG
ATTGGGGATCCGCTTGGAAAAGACCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAACGGTTTCAAT
GTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACAGACGCAGCAATTAATCCAGGTAACAGCGGCGGTCCTT
TGTTAAATACAGACGGCAAAATTGTCGGCATTAACAGTATGAAAATCAGTGAGGATGATGTTGAGGGTATCGGATTCGCC
ATTCCAAGCAATGACGTAAAACCGATTGCTGAAGAATTGCTGTCTAAAGGACAAATTGAACGTCCATATATCGGTGTCAG
CATGCTTGATCTAGAGCAAGTGCCGCAAAATTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGAATAAAGGCG
TTTACATCCGTGAGGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCGGAGGATATTATCATCGGCCTAAAA
GGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGATACCGTTGAAGTGAA
AATTCTCCGAAACGGCAAAGAAATGACGAAAAAAATTAAACTGGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(342-441)

Trypsin-like peptidase domain (Trypsin_2)

(160-304)

Peptidase family M50 (Peptidase_M50)

(366-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

41.045

89.532

0.367
  htrA Streptococcus pneumoniae D39

41.045

89.532

0.367
  htrA Streptococcus pneumoniae R6

41.045

89.532

0.367
  htrA Streptococcus pneumoniae TIGR4

41.045

89.532

0.367
  htrA Streptococcus mitis NCTC 12261

39.563

91.759

0.363