Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   OTB22_RS06300 Genome accession   NZ_CP113267
Coordinates   1240431..1242389 (-) Length   652 a.a.
NCBI ID   WP_000748873.1    Uniprot ID   A0A0B7M1B9
Organism   Streptococcus pneumoniae strain BC2     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1235431..1247389
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS06280 (OTB22_06285) - 1236159..1237325 (-) 1167 WP_000521381.1 MalY/PatB family protein -
  OTB22_RS06285 (OTB22_06290) - 1237333..1238427 (-) 1095 WP_000031974.1 cystathionine gamma-synthase -
  OTB22_RS06290 (OTB22_06295) - 1238584..1239306 (-) 723 WP_001010371.1 ABC transporter ATP-binding protein -
  OTB22_RS06295 (OTB22_06300) - 1239331..1240259 (-) 929 Protein_1252 ABC transporter ATP-binding protein -
  OTB22_RS06300 (OTB22_06305) amiA 1240431..1242389 (-) 1959 WP_000748873.1 peptide ABC transporter substrate-binding protein Regulator
  OTB22_RS06305 (OTB22_06310) - 1242593..1244215 (-) 1623 WP_000017793.1 polysaccharide biosynthesis protein -
  OTB22_RS06310 (OTB22_06315) - 1244321..1245766 (+) 1446 WP_000590310.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  OTB22_RS06315 (OTB22_06320) - 1245812..1246006 (-) 195 WP_000051201.1 CsbD family protein -
  OTB22_RS06320 (OTB22_06325) - 1246107..1246756 (-) 650 Protein_1257 DUF1803 domain-containing protein -
  OTB22_RS06325 (OTB22_06330) - 1246740..1247252 (-) 513 WP_000892261.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72561.97 Da        Isoelectric Point: 4.9968

>NTDB_id=761477 OTB22_RS06300 WP_000748873.1 1240431..1242389(-) (amiA) [Streptococcus pneumoniae strain BC2]
MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSL
AEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAK
NVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTS
DIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINF
ADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDS
SGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKR
YEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=761477 OTB22_RS06300 WP_000748873.1 1240431..1242389(-) (amiA) [Streptococcus pneumoniae strain BC2]
ATGAAAAAGTCTAAGAGCAAATATCTAACCTTGGCAGGTCTTGTCCTGGGTACAGGAGTTTTATTGAGCGCGTGTGGAAA
TTCTAGCACTGCATCAAAAACCTATAACTATGTTTATTCAAGTGATCCATCTAGTTTGAACTATCTAGCAGAAAACCGCG
CAGCAACATCCGATATTGTTGCAAATTTGGTAGACGGGTTATTAGAAAATGACCAATATGGGAATATTATTCCATCATTA
GCAGAGGATTGGACTGTTTCTCAGGACGGTTTGACCTATACCTACAAACTTCGTAAGGATGCCAAGTGGTTTACTTCTGA
GGGAGAAGAATATGCGCCTGTAACTGCCCAGGATTTTGTGACAGGTTTGCAATATGCAGCTGATAAAAAATCAGAAGCTT
TGTATCTAGTGCAGGACTCTGTTGCTGGTTTGGATGACTATATCACTGGTAAAACAAGCGACTTTTCAACTGTCGGTGTC
AAGGCACTTGATGACCAAACGGTTCAATATACTTTGGTTAAACCAGAACTTTACTGGAATTCAAAAACACTTGCAACGAT
ACTTTTTCCTGTTAATGCAGATTTCCTGAAATCAAAAGGGGATGATTTTGGGAAGGCGGATCCATCTAGTATTTTGTACA
ATGGACCTTTCTTGATGAAAGCACTTGTCTCAAAATCTGCTATTGAATATAAGAAAAACCCTAATTACTGGGATGCTAAG
AATGTCTTTGTAGACGATGTGAAATTGACCTACTATGATGGTAGCGACCAAGAATCACTGGAACGTAATTTTACAGCTGG
TGCTTATACTACGGCTCGTCTTTTTCCTAACAGCTCCAGCTATGAAGGGATTAAAGAAAAATACAAAAACAATATCATCT
ATAGTATGCAAAATTCAACTTCATATTTCTTTAATTTTAACCTAGATAGGAAGTCTTACAATTATACTTCTAAAACAAGT
GACATTGAAAAGAAATCGACTCAGGAAGCAGTTCTCAATAAAAACTTCCGTCAGGCTATCAATTTTGCTTTTGACAGAAC
ATCTTATGGGGCTCAGTCTGAAGGGAAAGAAGGTGCAACAAAGATTTTGCGTAACCTAGTGGTTCCTCCAAACTTTGTCA
GTATCAAGGGAAAAGACTTTGGTGAAGTTGTAGCCTCTAAGATGGTCAACTATGGTAAGGAATGGCAAGGTATCAACTTT
GCGGATGGTCAAGACCCTTACTACAATCCTGAGAAAGCCAAGGCTAAGTTTGCGGAAGCTAAGAAAGAACTCGAAGCAAA
GGGTGTTCAATTCCCAATCCACTTGGATAAGACTGTGGAAGTAACAGATAAAGTAGGCATACAAGGAGTTAGTTCTATCA
AACAATCAATTGAATCTGTTTTAGGTTCTGATAATGTAGTGATTGACATTCAGCAATTAACATCAGATGAGTTTGACAGT
TCAGGCTACTTTGCTCAAACAGCTGCTCAGAAAGACTATGATTTATATCATGGCGGTTGGGGACCTGATTATCAAGACCC
GTCAACCTATCTCGATATTTTTAATACTAATAGTGGAGGATTTCTGCAAAATCTTGGACTAGAGCCTGGTGAGGCCAATG
ACAAGGCTAAGGCAGTTGGACTGGATGTCTATACTCAAATGTTGGAAGAAGCTAATAAAGAGCAAGATCCAGCCAAACGT
TATGAGAAATATGCTGATATTCAAGCTTGGTTGATTGATAGTTCTTTAGTTCTTCCAAGTGTTTCGCGTGGGGGAACACC
ATCATTGAGAAGAACCGTACCATTTGCTGCTGCCTATGGTTTAACCGGTACAAAAGGGGTTGAATCATATAAATACCTCA
AAGTACAAGATAAGATTGTCACAACAGACGAATATGCAAAAGCCAGAGAAAAATGGTTGAAAGAAAAAGAAGAATCCAAT
AAAAAAGCCCAAGAAGAATTGGCAAAACATGTCAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M1B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

56.422

100

0.566
  amiA3 Streptococcus thermophilus LMD-9

55.878

100

0.561
  amiA3 Streptococcus thermophilus LMG 18311

55.725

100

0.56