Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   OTU45_RS06210 Genome accession   NZ_CP113114
Coordinates   1248783..1250132 (-) Length   449 a.a.
NCBI ID   WP_000886213.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1243783..1255132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS06185 (OTU45_06185) - 1245318..1246304 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  OTU45_RS06190 (OTU45_06190) - 1246593..1247336 (-) 744 WP_001037000.1 potassium channel family protein -
  OTU45_RS06195 (OTU45_06195) - 1247383..1247637 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE family toxin -
  OTU45_RS06200 (OTU45_06200) relB 1247639..1247881 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  OTU45_RS06205 (OTU45_06205) vicX 1247972..1248781 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  OTU45_RS06210 (OTU45_06210) micB 1248783..1250132 (-) 1350 WP_000886213.1 cell wall metabolism sensor histidine kinase VicK Regulator
  OTU45_RS06215 (OTU45_06215) micA 1250125..1250829 (-) 705 WP_000722076.1 response regulator YycF Regulator
  OTU45_RS06220 (OTU45_06220) mutY 1250885..1252060 (-) 1176 WP_000886152.1 A/G-specific adenine glycosylase -
  OTU45_RS06225 (OTU45_06225) - 1252157..1252282 (+) 126 WP_001818232.1 hypothetical protein -
  OTU45_RS06230 (OTU45_06230) - 1252388..1254058 (-) 1671 WP_000845285.1 formate--tetrahydrofolate ligase -
  OTU45_RS06235 (OTU45_06235) coaB 1254288..1254977 (+) 690 WP_000699495.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51688.43 Da        Isoelectric Point: 4.9098

>NTDB_id=760337 OTU45_RS06210 WP_000886213.1 1248783..1250132(-) (micB) [Streptococcus pneumoniae strain NP1]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSLLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=760337 OTU45_RS06210 WP_000886213.1 1248783..1250132(-) (micB) [Streptococcus pneumoniae strain NP1]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACCAACCGTCGGGGTCAGATTATCATGATTAATGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGAGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCTCCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(98-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.555

100

0.996
  vicK Streptococcus mutans UA159

69.652

89.532

0.624